رابطه میان غلظت substance p و calcitonin gene related peptide با لثه نواحی مختلف دندانی

رابطه میان غلظت Substance P و Calcitonin Gene Related Peptide با لثه نواحی مختلف دندانی

زمینه و هدف: در مورد علت درگیری بعضی نواحی خاص لثه (نواحی دندان های 1 بالا و6 بالا و پایین) در برخی بیماری های پریودنتال، هیچ توجیه قابل توجهی عنوان نشده است. با توجه به این که مناطق یاد شده نزدیک فورامن های محل گذر اعصاب قرار دارند و با توجه به این که نوروپپتیدها که از انتهای اعصاب آزاد می شوند، نقش مهمی در برانگیختن التهاب دارند، همچنین از آنجایی که به نقش SP و CGRP در بیماری های پریودنتال اش...

Osteotropic effects by the neuropeptides calcitonin gene-related peptide, substance P and vasoactive intestinal peptide.

Immunohistochemical phenotypic characterization of skeletal nerve fibers has demonstrated the expression of a restricted number of neuropeptides, including calcitonin gene-related peptide (CGRP), substance P (SP) and vasoactive intestinal peptide (VIP). According to the neuro-osteological hypothesis, such neuropeptides can be released and exert paracrine biological effects on bone cells present...

Calcitonin gene related peptide.

Role of calcitonin gene-related peptide and substance P in Dahl-salt hypertension.

Calcitonin gene-related peptide (CGRP) and substance P are known to play a counterregulatory role in acquired models of salt-dependent hypertension. In contrast, neuronal production of these peptides is decreased in the spontaneously hypertensive rat, which may contribute to the elevated blood pressure. To determine the role played by CGRP and substance P in Dahl-salt hypertension, 4- to 6-week...

Visceral targets specify calcitonin gene-related peptide and substance P enrichment in trigeminal afferent projections.

Rat trigeminal ganglion projections to a visceral target (intracranial blood vessels) are enriched in calcitonin gene-related peptide (CGRP) and substance P (Sub P) compared to trigeminal ganglion projections to a cutaneous target (the forehead skin). We asked if transplants of a novel visceral target (fetal stomach antrum tissue) into the path of the neonatal rat trigeminal frontal nerve proje...

Substance P and calcitonin gene-related peptide intrinsic choroidal neurons in human choroidal whole-mounts.

To determine the presence in the human choroid of substance P (SP)-and calcitonin gene-related peptide (CGRP) positive intrinsic choroidal neurons (ICNs), choroidal whole-mounts were processed for indirect immunofluorescence. An antibody to a component of the neuronal cytoskeleton, neurofilament 200 kDa (NF-200), was combined with antibodies to SP and to CGRP (neuropeptides proper to the sensor...