comparative efficacy of dexamethasone versus hydrocortisone in severe acute pediatric asthma
نویسندگان
چکیده
this study aimed to compare the efficacy of dexamethasone and hydrocortisone in the treatment of acute paediatric asthma. forty seven asthmatic children were randomised to receive either dexamethasone (0.6 mg/ml, maximum 16 mg) in a single dose or hydrocortisone (8-10 mg/kg/day) in 4 equal doses for 2 days. our findings showed that the mean length of hospitalization in children receiving dexamethasone was significantly shorter than those receiving hydrocortisone.
منابع مشابه
Comparative efficacy of dexamethasone versus hydrocortisone in severe acute pediatric asthma.
This study aimed to compare the efficacy of dexamethasone and hydrocortisone in the treatment of acute paediatric asthma. Forty seven asthmatic children were randomised to receive either dexamethasone (0.6 mg/ml, maximum 16 mg) in a single dose or hydrocortisone (8-10 mg/kg/day) in 4 equal doses for 2 days. Our findings showed that the mean length of hospitalization in children receiving dexame...
متن کاملAcute hydrocortisone myopathy in acute severe asthma.
Myopathy of insidious onset produced by corticosteroids is well recognised. In recent years acute myopathy has been reported in patients with acute severe asthma treated with 3-4 g of intravenous hydrocortisone a day.1 2 It has been argued that to minimise the risks of this the dose should be no more than 1 g of hydrocortisone a day.2 There is evidence that 1 g/day is an effective regimen.3 We ...
متن کاملA cost-effectiveness analysis of dexamethasone versus prednisone in pediatric acute asthma exacerbations.
OBJECTIVES The objective was to evaluate the cost-effectiveness of dexamethasone versus prednisone for the treatment of pediatric asthma exacerbations in the emergency department (ED). METHODS This was a cost-effectiveness analysis using a decision analysis model to compare two oral steroid options for pediatric asthma patients: 5 days of oral prednisone and 2 days of oral dexamethasone (with...
متن کاملThe efficacy of ketamine in pediatric emergency department patients who present with acute severe asthma.
STUDY OBJECTIVE We determine whether a continuous infusion of ketamine can decrease the severity of a moderately severe acute asthma exacerbation by a clinically significant 2 points using a 15-point Pulmonary Index scoring scale. METHODS A double-blinded, randomized, placebo-controlled trial was performed to evaluate patients aged 2 to 18 years who presented to a pediatric emergency departme...
متن کاملUse of dexamethasone and prednisone in acute asthma exacerbations in pediatric patients.
QUESTION Children frequently present to my rural emergency department with asthma exacerbations. Should I prescribe systemic corticosteroids? If so, which systemic corticosteroid should I prescribe? ANSWER A short course of steroids is indicated in the treatment of asthma exacerbations. Both prednisone (1 to 2 mg/kg daily for 5 days) and dexamethasone (0.3 to 0.6 mg/kg daily for 1 to 5 days) ...
متن کاملAcute severe asthma.
Introduction Acute severe asthma is one of the most common causes of visits to hospital emergency departments worldwide and accounts for the greater part of the economic and healthcare burden of the disease.1 Failure to appreciate the severity, inadequate emergency treatment, and delay in referral may lead to increased mortality and morbidity.2 Asthma is the most common respiratory emergency in...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of allergy, asthma and immunologyجلد ۶، شماره ۳، صفحات ۱۵۹-۱۶۰
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023