clinical evaluation of 38 patients with juvenile myoclonic epilepsy.
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Clinical Evaluation of 38 Patients with Juvenile Myoclonic Epilepsy
Juvenile myoclonic epilepsy (JME) is one of the most common age-related idiopathic generalized epilepsies and includes about 5%-10% of all kinds of epilepsy (1). It presents as a combination of myoclonic jerks (in all cases), generalized tonic-clonic seizures (GTCS) (in more than 80-97% of the cases), absence seizures (2) and its inheritance is a complicated process. Epileptic seizures typicall...
متن کاملTreatment of myoclonic seizures in patients with juvenile myoclonic epilepsy
Drug treatment of Juvenile myoclonic epilepsy (JME) is mainly based on clinical experience and prospective and retrospective studies, with little evidence from randomized clinical trials. There are no head-to-head comparisons between old and new antiepileptic drugs (AEDs) and no drugs licensed specifically for JME. Valproate is unquestionably the drug of the first choice in men with JME. In wom...
متن کاملTopiramate in patients with juvenile myoclonic epilepsy.
BACKGROUND Topiramate is a broad-spectrum agent effective against primarily generalized tonic-clonic seizures (PGTCS) as well as partial-onset seizures. Juvenile myoclonic epilepsy is one of the most common idiopathic generalized epilepsies, with most patients experiencing PGTCS. OBJECTIVE To evaluate topiramate as add-on therapy in patients with juvenile myoclonic epilepsy. DESIGN Post-hoc...
متن کاملClinical genetic study in juvenile myoclonic epilepsy
PURPOSE To evaluate clinical features of probands with juvenile myoclonic epilepsy (JME) and affected members of their families in order to study clinical genetics of JME. METHOD Thirteen unrelated families with at least two members with history of seizures were identified; clinical and genealogic data were collected from JME probands and family members. RESULTS All probands had myoclonic a...
متن کاملJuvenile myoclonic epilepsy.
2. In treatment of juvenile myoclonic epilepsy, the following is true except: a. Phenobarbitone is an effective treatment for generalized tonic seizures and myoclonic seizures b. Lamotrigine exaggerates myoclonic seizures in 50% of patients c. Levetiracetam has potent antimyoclonic effects d. Life long treatment with a proper AED is recommended for juvenile myoclonic epilepsy e. Pregabalin is a...
متن کامل[Juvenile myoclonic epilepsy].
CONCLUSION We conclude that despite inevitable variability the clinical picture of JME is characteristic. It is easy to diagnose JME if one thinks of it while the history should be thoroughly analyzed. An EEG recording during sleep confirms the diagnosis. An early diagnosis of JME permits adequate prognosis of the subsequent course of epilepsy, and adequate therapy brings remission in most of t...
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عنوان ژورنال:
iranian journal of public healthجلد ۴۳، شماره ۵، صفحات ۶۹۱-۲
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