albuminuria in diabetic patients before and after fetal liver-de¬rived cell suspension allotransplantion: a 24 months fol¬low up study

نویسندگان

rezvan razmandeh

ali tootee

farideh razi

camelia rambod

چکیده

background: stem-cell therapy plays a preventive role for different complications of diabetes, including diabetes nephropathy. the current phase 3 single-arm clinical trial is designed to investigate the potential protective effect of allotransplantation of fetal liver-derived cell suspension in diabetic nephropathy. methods: seventy-four diabetic patients with type 1 were selected according to the inclusion criteria defined and underwent the procedure of transplantation fetal liver-derived stem-cells. patients were followed for a period on 24 months and indicators of diabetes and diabetes nephropathy (hba1c, acr, cr and gfr) were monitored during the whole time. statistical analysis was conducted with spss vers.16 and one-way repeated measure anova was used. results: the gfr values significantly increased during the 24 months period of follow up. conclusion: stem-cell therapy can play a significant protective role in prevention from diabetic nephropathy.

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عنوان ژورنال:
iranian journal of public health

جلد ۴۴، شماره ۲، صفحات ۴۲-۴۷

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