lipid variables related to the extent and severity of coronary artery disease in non-diabetic turkish cypriots

background: we aimed to analyze the association between lipid variables and the extent and severity of coronary artery disease (cad) in non-diabetic turkish cypriots. methods: overall, 412 patients (mean (sd) age: 58.8 (10.5) yr, 50.1% male) who underwent diagnostic coronary angiography were included in this single-center, cross-sectional study. the friesinger index (fi) was used to assess the extent and severity of cad. the lipid variables [total cholesterol, ldl-c, hdl-c, triglyceride (tg) levels and the tg/hdl-c ratio] were categorized into quartiles and evaluated regarding extensive/severe cad. potential risk factors in the turkish cypriot cohort were evaluated as predictors of cad in univariate and multivariate logistic regression models. the population of this study are non-diabetic turkish cypriots which are administrated north cyprus. results: the mean (sd) friesinger index was 6.9 (4.4), and 59.0% of the patients exhibited a friesinger index category of ≥5. in the univariate analysis, extensive/severe cad was directly related to total triglycerides ( p =0.01) and tg/hdl-c quartiiles ( p =0.001) and inversely related to hdl-c quartiles ( p =0.001). in the multivariate model, diabetes (or: 4.9; 95% ci: 1.3 - 19.2; p =0.02), male gender (or: 3.1; 95% ci: 0.95 - 10.3; p =0.06) and high tg/hdl-c ratio (or: 2.2; 95% ci: 1.3 - 3.8; p =0.004 in the overall population and or: 1.9; 95% ci: 1.4 - 2.3; p =0.003 except diabetics) were the significant predictors of cad. conclusion: we found a significant relationship between the lipid quartiles and the extent and severity of cad based on the friesinger index. male gender, co-morbid diabetes and the tg/hdl-c ratio also played significant roles in predicting cad risk in non-diabetic turkish cypriots.