clinical problem: cancer biopsy

Clinical Problem: Cancer Biopsy

A letter to the editor entitled “Cancer Biopsy in Ancient Persian Medicine: Do or Not to Do!” was published in Iran J Public Health (1). I would like to focus attention on authors’ suggestion for using non-invasive methods such as laboratory parameters and biomarkers, for tumor detection. Advancements in oncology resulted in development of different protocols for cancer treatment. Accordingly, ...

Liquid biopsy genotyping in lung cancer: ready for clinical utility?

Liquid biopsy is a blood test that detects evidence of cancer cells or tumor DNA in the circulation. Despite complicated collection methods and the requirement for technique-dependent platforms, it has generated substantial interest due, in part, to its potential to detect driver oncogenes such as epidermal growth factor receptor (EGFR) mutants in lung cancer. This technology is advancing rapid...

Renal Biopsy: Clinical Correlations

Clinical merit of endomyocardial biopsy.

At this time, endomyocardial biopsy has proven validity as a diagnostic method in few circumstances. However, it is overused. In the near term, the extent of its use should be modified by knowledge of its therapeutic relevance in patients with myocarditis. In the long term, numerous new techniques for studying pathophysiology at the subcellular and molecular levels will demand a central role fo...

Negative Biopsy after Referral for Biopsy-Proven Gastric Cancer

BACKGROUND/AIMS Repeat endoscopy with biopsy is often performed in patients with previously diagnosed gastric cancer to determine further treatment plans. However, biopsy results may differ from the original pathologic report. We reviewed patients who had a negative biopsy after referral for gastric cancer. METHODS A total of 116 patients with negative biopsy results after referral for biopsy...

Liquid Biopsy in Pancreatic Cancer

Submit Manuscript | http://medcraveonline.com Abbreviations: PDA: Pancreatic Ductal Adenocarcinoma; CTCs: Circulating Tumor Cells; ctDNA: Circulating Tumor DNA; EXV: Extracellular Vesicles; NGS: Next Generation Sequencing; OS: Overall Survival; EpCAM: Epithelial-Cell Adhesion Molecule; NE-iFISH: Negative Enrichment Method Coupled to Immunofluorescence in Situ Hybridization; ddPCR: Digital Dropl...