prenatal acute stress attenuated epileptiform activities in neonate mice

Prenatal Acute Stress Attenuated Epileptiform Activities in Neonate Mice

Objective: Development of the central nervous system (CNS) is dependent on interactions between genetic and epigenetic factors, some of which could affect the susceptibility of the developing brain to damaging insults. Gestational stress has been shown as a potential factor associated with higher risk of developing certain neurological and psychiatric disorders. This study tested the hypothesis...

Hypertensive response to acute stress is attenuated in interleukin-6 knockout mice.

This study tested the hypothesis that the inflammatory cytokine, interleukin-6, contributes to the hypertensive response to acute psychosocial stress, caused by switching male mice to a cage previously occupied by a different male mouse. Male C57BL6 (WT) and interleukin-6 (IL-6) knockout (KO) mice were implanted with biotelemetry devices to monitor mean arterial pressure, heart rate, and motor ...

Assessment of oxidative stress parameters of brain-derived neurotrophic factor heterozygous mice in acute stress model

Objective(s): Exposing to stress may be associated with increased production of reactive oxygen species (ROS). Therefore, high level of oxidative stress may eventually give rise to accumulation of oxidative damage and development of numerous neurodegenerative diseases. It has been presented that brain-derived neurotrophic factor (BDNF) supports neurons against various neurodegenerative conditio...

Effects of Prenatal Lipopolysaccharide Exposure on Reproductive Activities and Serum Concentrations of Pituitary-Gonadal Hormones in Mice Offspring

Some acute phase proteins, oxidative stress biomarkers and antioxidant enzyme activities in ewes with pregnancy toxemia

The aim of this study is to investigate antioxidant enzymes, oxidative stress biomarkers and the acute phase proteins levels for subclinical and clinical pregnancy toxemia and to determine the effect of early diagnosis on the success of curing. According to the results of clinical and biochemical parameters, from 39 ewes, 10 were healthy ewes (control group), 13 ewes had subclinical pregnancy t...

Antidiabetic and antineuropathic effect of Onosma dichroanthum extract on acute stress in STZ diabetic mice

Background and objectives: Diabetes is a metabolic disease with hyperglycemia, decrease in insulin secretion or de-sensitization of peripheral cells to insulin.Onosmadichroanthum is a species of Boraginaceae and is used in traditional medicine for its anti-oxidant, anti-inflammatory and antibiotic properties, however data on its anti-diabetic effects ...