depth dose calculation of holmium-166 for different shape source by varskin3 code
نویسندگان
چکیده
introduction: using beta emitter radionuclide is a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. the aim of this research is to evaluate the tissue response to beta rays of 166ho and determine the feasibility of beta emitting radionuclide for treatment of skin cancers. methods: in this work, we have calculated depth dose distribution of 166ho using varskin3 code. the code has been run for various input parameters to calculate absorbed depth dose for different shape of source. results: absorbed depth dose variation has been calculated for166ho beta emitter, in different shape of sources such as slab, spherical, cylindrical and 2-d disk shapes. comparison of the result for different shape sources has been presented. conclusion: the result shows that 2-d disk source induces damage to skin cells more than other shape of sources. these computational and lee et al. experimental results are shown that 166ho radionuclide treatment is very useful for skin cancer therapy. one of advantages of using 166ho radionuclide is that no adverse effect on underlying bone and soft tissue due to the physical characteristics of beta rays, high linear energy transfer or rapid depth dose fall off is observed.
منابع مشابه
Depth dose calculation of Holmium-166 for different shape source by VARSKIN3 code
Introduction: Using beta emitter radionuclide is a useful therapeutic modality in the treatment of skin cancers in areas which are difficult to cure by other methods. The aim of this research is to evaluate the tissue response to beta rays of 166Ho and determine the feasibility of beta emitting radionuclide for treatment of skin cancers. Methods: In this...
متن کاملNew formula for Calculation of Cobalt-60 Percent Depth Dose
Introduction: On the basis of percent depth dose (PDD) calculation, the application of dosimetry in radiotherapy has an important role to play in reducing the chance of tumor recurrence. The aim of this study is to introduce a new formula for calculating the centeral axis percent depth doses of Cobalt-60 beam. Materials and Methods: In the present study, based on ...
متن کاملCalculation of depth dose profiles with a track structure code
A prerequisite for applying high-LET radiation like protons or carbon ions to patients is the precise knowledge of absorbed dose, specifically the depth dose distribution. The legal restraints imposed by the authorities requires the Bragg peak position to be reproduced within 0.5 mm and the calculated absorbed dose distribution to agree within 5% (on average) with the measurements. These condit...
متن کاملnew formula for calculation of cobalt-60 percent depth dose
introduction: on the basis of percent depth dose (pdd) calculation, the application of dosimetry in radiotherapy has an important role to play in reducing the chance of tumor recurrence. the aim of this study is to introduce a new formula for calculating the centeral axis percent depth doses of cobalt-60 beam. materials and methods: in the present study, based on ...
متن کاملProduction of Holmium-166 DOTMP: A promising agent for bone marrow ablation in hematologic malignancies
Intoduction: Therapeutic radiopharmaceuticals are radiolabeled molecules to deliver sufficient doses of ionizing radiation to specific disease sites such as bone metastases, brain and liver tumors and bone marrows malignancies including multiple myeloma. Among some therapeutic radiopharmaceuticals, 166Ho-1,4,7,10 -tetraazacyclo dodecane-1,4,7,10 tetraethy...
متن کاملX-ray spectra calculation for different target-filter of mammograms using MCNP Code
ABSTRACTBackground: An electron beam generated X-ray spectrum consists of characteristic X-ray and continuous bermsstrahlung. The aim of this research is calculating and comparing X-ray spectra for different target filter of mammograms. Materials and Methods: Monte Carlo is a very powerful tool to simulate a series of different target-filter assembly in order to calculate the X-ray spectra. MC...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of nuclear medicineناشر: tehran university of medical sciences
ISSN 1681-2824
دوره 18
شماره 1 2010
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023