evaluation of strontium-89 in palliative treatment of widespread and painful bone metastases due to breast and prostate cancer [persian]
نویسندگان
چکیده
treatment of bone metastases comprises over 10% of the workload of a radiation-oncology center. bone metastases produce severe pain and immobility, necessitate narcotic use, and reduce the quality of life. a good palliative treatment must be complete, free from side effects and fast; thus we decided to evaluate strontium-89 (89sr) effectivity for palliation of breast and prostate cancer bone metastases in relation to above factors. the use of 89sr radionuclide therapy started on 1992 in radiation-oncology department of cancer institute. until early 1999, 91 patients with bone metstases have been treated for pain relief in our department with 4 mci of 89sr. of these, 80 were breast and prostate metastatic cancers. 35 patients came back for follow-up and were completely evaluated. response was seen in 65% of patients (complete response in 40% and partial response in 25%). side effects were negligible, and quality of life of the responding patients significantly increased. there was no significant relationship between the type of primary cancer or patient age and response. in conclusion, treatment of metastatic bone cancer from prostate and breast primaries in our department was effective, with a relatively high rate of response and no serious side effects.
منابع مشابه
Evaluation of Strontium-89 in palliative treatment of widespread and painful bone metastases due to breast and prostate cancer [Persian]
Treatment of bone metastases comprises over 10% of the workload of a radiation-oncology center. Bone metastases produce severe pain and immobility, necessitate narcotic use, and reduce the quality of life. A good palliative treatment must be complete, free from side effects and fast; Thus we decided to evaluate Strontium-89 (89Sr) effectivity for palliation of breast and prostate cancer b...
متن کاملStrontium-89 Therapy in Painful Bony Metastases
Strontium-89 (Sr), a bone-seeking radiopharmaceutical, has been used successfully in recent trials to palliate bone pain secondary to metastatic disease. The use of this beta emitter in systemic radionuclide therapy should become an integral part in the management of many patients with metastatic disease to the bone. Intravenous Sr may be used in conjunction with standard chemotherapy and exter...
متن کاملthe study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region
چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولa synchronic and diachronic approach to the change route of address terms in the two recent centuries of persian language
terms of address as an important linguistics items provide valuable information about the interlocutors, their relationship and their circumstances. this study was done to investigate the change route of persian address terms in the two recent centuries including three historical periods of qajar, pahlavi and after the islamic revolution. data were extracted from a corpus consisting 24 novels w...
15 صفحه اولRadiotherapy in palliative treatment of painful bone metastases
Received 4 April 2009 Accepted 25 August 2009 Correspondence to: Andreja Gojkovič Horvat, M.D., Department of Radiation Oncology, Institute of Oncology Ljubljana, Zaloška 2, SI-1000 Ljubljana, Slovenia. Phone: +386 1 5879 110; Fax: + 386 1 5879 400; E-mail: [email protected] types of cancer with systemic dissemination, especially breast cancer, prostate and lung cancer, with the incidence of ...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
iranian journal of nuclear medicineناشر: tehran university of medical sciences
ISSN 1681-2824
دوره 8
شماره 1 2000
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023