clinicopathological study in an ovine model of experimental acute myocardial infarction

to evaluate the prognostic significance of clinicopathological measurement in the diagnosis of acute myocardial infarction (mi) in sheep, acute mi was induced by ligation of left anterior descending coronary artery (lad). for this purpose, twenty four healthy sheep were divided into the sham-operated or control group (group i, thoracotomy without mi) and the experimental group (group ii, with mi) (n=12 in each), then all animals were subjected to the echocardiographic and clinicopathological analysis 2 days post-mi. echocardiography revealed significant differences in left ventricular end-diastolic diameter (lvedd), lv end-systolic diameter (lvesd), lv ejection fraction (lvef) and lv fractional shortening (lvfs) between groups (p