nonalcoholic steatohepatitis: an expanded clinical entity

نویسندگان

mohammadjafar farahvash

چکیده

nonalcoholic steatohepatitis: an expanded clinical entity

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Nonalcoholic steatohepatitis.

Nonalcoholic fatty liver disease (NAFLD) is being increasingly recognized as a common liver disorder that represents the hepatic manifestation of the metabolic syndrome, a variably defined aggregate of disorders related to obesity, insulin resistance, type II diabetes, hypertension and hyperlipidemia. Nonalcoholic steatohepatitis (NASH) is the progressive form of liver injury that carries a ris...

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Nonalcoholic Steatohepatitis: Diagnostic Challenges.

This article reviews diagnostic criteria for nonalcoholic steatohepatitis (NASH), current grading and staging methodology, and diagnostic challenges and pitfalls in routine practice. Current practice guidelines and prognostic and treatment considerations are discussed. The clinical diagnosis of nonalcoholic fatty liver disease may represent stable disease without progressive liver damage, in th...

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Necroptosis in Nonalcoholic Steatohepatitis

Figure 1. Necroptosis is activated in human nonalcoholic steatohepatitis (NASH) samples. Representative immunohistochemical staining for phospho-MLKL on livers from different controls (Ctl) and NASH patients. Note the specific granular cytoplasmatic staining. See Gautheron et al for the specifics of the NASH cohort as well as the technical and ethical aspects. Dear Editor: One fundamental step ...

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Model of nonalcoholic steatohepatitis.

BACKGROUND Obesity and diabetes are frequently associated with nonalcoholic steatohepatitis (NASH), but studies have been hampered by the absence of a suitable experimental model. OBJECTIVE Our objective was to create a rat model of NASH. DESIGN Sprague-Dawley rats were fed a high-fat, liquid diet (71% of energy from fat, 11% from carbohydrates, 18% from protein) or the standard Lieber-DeCa...

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Pioglitazone in nonalcoholic steatohepatitis.

*KURAに登録されているコンテンツの利用については,著作権法に規定されている私的使用や引用などの範囲内で行ってください。 *著作権法に規定されている私的使用や引用などの範囲を超える利用を行う場合には,著作権者の許諾を得てください。ただし,著作権者 から著作権等管理事業者(学術著作権協会,日本著作出版権管理システムなど)に権利委託されているコンテンツの利用手続については ,各著作権等管理事業者に確認してください。 Title Pioglitazone in Nonalcoholic Steatohepatitis Author(s) Ota, Tsuguhito; Takamura, Toshinari; Kaneko, Shuichi Citation New England Journal of Medicine, 356(10): 1067-1069 Issue Date 20...

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جلد ۲، شماره ۹&۱۰، صفحات ۳-۰

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