efficacy of transarterial chemoembolization on lesion reduction in colorectal liver metastases

نویسندگان

hossein ghanaati department of radiology, advanced diagnostic and interventional radiology research center, medical imaging center, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

vahid mohammadzadeh medical student, tehran university of medical sciences, tehran, iran.

ali mohammadzadeh department of radiology, rajaie cardiovascular medical and research center, tehran university of medical sciences, tehran, iran.

kavous firouznia department of radiology, advanced diagnostic and interventional radiology research center, medical imaging center, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

چکیده

following failure of systemic chemotherapy, transarterial chemoembolization (tace) is an available method to control unresectable liver metastases from colorectal carcinoma (crc). the aim of present study was to evaluate the efficacy of chemoembolization for inoperable metastatic liver lesions from crc. forty-five crc patients with liver metastases resistant to systemic chemotherapy were enrolled in our study. for each patient, three session of tace were conducted with 45 days interval. a combination of mitomycin, doxorubicin, and lipiodol were used for tace. a tri-phasic computed tomography scan and biochemical laboratory tests were performed for all patients at baseline and 30 days after each tace. image analysis included measurement of lesion diameters as well as contrast enhancement. eleven patients deceased before completing three session and the final analyses were performed on the remaining 34 patients. evaluation of a total 93 lesions in all patients after chemoembolization sessions revealed a 25.88% reduction in anteroposterior (ap) diameter, 33.92% transverse (t) diameter, and 42.22% in product of apxt diameter of lesions (p

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Efficacy of transarterial chemoembolization on lesion reduction in colorectal liver metastases.

Following failure of systemic chemotherapy, transarterial chemoembolization (TACE) is an available method to control unresectable liver metastases from colorectal carcinoma (CRC). The aim of present study was to evaluate the efficacy of chemoembolization for inoperable metastatic liver lesions from CRC. Forty-five CRC patients with liver metastases resistant to systemic chemotherapy were enroll...

متن کامل

Transarterial chemoembolization with irinotecan beads in the treatment of colorectal liver metastases: systematic review.

PURPOSE For patients with unresectable colorectal liver metastasis (CRLM), transarterial embolization with the use of drug-eluting beads with irinotecan (DEBIRI) represents a novel alternative to systemic chemotherapy or local treatments alone. The present systematic review evaluates available data on the efficacy and safety of DEBIRI embolization. MATERIALS AND METHODS A comprehensive search...

متن کامل

Chemoembolization in colorectal liver metastases: the rebirth.

Currently image-guided trans-arterial chemoembolization (TACE) has a significant role in the therapy of patients with hepatocellular carcinoma and liver metastases. This endovascular hepatic-directed therapy offers the dual benefit of true local neoplastic control and reduction of side-effects. As a result, it has been included in the guidelines for primary liver cancer and is often considered ...

متن کامل

Transarterial chemoembolization using DEBIRI for treatment of hepatic metastases from colorectal cancer.

BACKGROUND/AIM Dismal survival rates of metastatic colorectal cancer (mCRC) to the liver have been recorded. Transarterial chemoembolization (TACE) with irinotecan eluting beads (DEBIRI) may be a safe palliative treatment with fewer serious adverse effects (SAEs). We aimed to establish the safety and efficacy of DEBIRI TACE in the treatment of hepatic metastases from colorectal cancer (CRC). ...

متن کامل

Liver Abscess Formation Following Transarterial Chemoembolization

To investigate the clinical features, risk factors, and bacterial spectrum of liver abscess following transarterial chemoembolization (TACE) and evaluate the therapeutic effect of percutaneous catheter drainage (PCD) on the abscesses.A retrospective review of patient charts was performed in 3613 patients who suffered from liver malignancies (2832 patients with hepatocellular carcinoma and 781 w...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
acta medica iranica

جلد ۵۰، شماره ۸، صفحات ۵۳۵-۵۴۰

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023