effects of coenzyme q10 on ldl oxidation in vitro
نویسندگان
چکیده
coenzyme q10, a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. the present study investigated the effects of coenzyme q10 on in vitro ldl oxidation quantitavely. the formation of conjugated dienes, malondialdehyde (mda) and electrophoretic mobility were monitored as markers of the oxidation of ldl, respectively. coenzyme q₁₀ showed a decrease the formation of conjugated dienes and mda, respectively, against oxidation in vitro. coenzyme q₁₀ also reduced electrophoretic mobility of the oxidized human ldl. thus, results showed that the coenzyme q10 exhibits strong antioxidant activity in cuso₄-mediated oxidation of ldl (p
منابع مشابه
Effects of coenzyme Q(10) on LDL oxidation in vitro.
Coenzyme Q(10), a lipid soluble benzoquinone, has excellent antioxidant and membrane stabilizing properties in the cardiac tissue. The present study quantitatively investigated the effects of coenzyme Q(10) on in vitro LDL oxidation. The formation of conjugated dienes, malondialdehyde (MDA) and electrophoretic mobility were monitored as markers of the oxidation of LDL, respectively. Coenzyme Q(...
متن کاملمقایسه اثرات عصاره ساچوریاخوزستانیکا، ویتامین E ،کوآنزیم Q10 بر پراکسیداسیون LDL درمحیط In vitro
Oxidation of low-density lipoprotein (LDL) has been strongly suggested as a key factor in the pathogenesis of atherosclerosis. Thus the inclusion of some anti-oxidant compounds such as Satureja Khozistanica,vitamin E and coenzyme Q10 in daily dietary food stuff may inhibit the production of oxidized LDL and may decrease both the development and the progression of atherosclerosis. The present st...
متن کاملEffect of coenzyme Q10 on radiation-induced fatigue in rats
Background: Fatigue is a common side effect in cancer patients undergoing radiation therapy (RT). Radiation-induced fatigue affects the quality of life, but there is no definitive treatment option. In this study, the weight-loaded forced swim test was performed to assess the effect of coenzyme Q10 (CoQ10) on radiation-induced fatigue. Materials and Methods: A total of 60 rats were divided rando...
متن کاملCoenzyme Q10 effects in neurodegenerative disease
Coenzyme Q10 (CoQ10) is an essential cofactor in the mitochondrial respiratory chain, and as a dietary supplement it has recently gained attention for its potential role in the treatment of neurodegenerative disease. Evidence for mitochondrial dysfunction in neurodegenerative disorders derives from animal models, studies of mitochondria from patients, identification of genetic defects in patien...
متن کاملEffects of Coenzyme Q10 on Blood Biochemistry in Rats
CoenzymeQ10 (CoQ10) is used as a food supplement and as an ethical drug because of its antioxidant functions and key role in mitochondrial bioenergetics. In this study, the effects of CoQ10 on blood biochemistry and malondialdehyde (MDA) levels in rats were investigated. Ten male Wistar rats ages ranging between 7 and 8 weeks were used. All animals were kept under the same condition and were gi...
متن کاملEffects of Coenzyme Q10 Level on Clinical Parameters in Cystic Fibrosis Patients
Background: Cystic Fibrosis (CF) is a hereditary autosomal recessive genetic disorder that can affect many organs including the lungs and the digestive system. We aimed to assess the effects of coenzyme Q10 level on clinical parameters in cystic fibrosis patients. Materials and Methods This cross-sectional study was performed on 40 patients (13 females and 19 males) with cystic fibrosis who wer...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
acta medica iranicaجلد ۵۱، شماره ۱، صفحات ۱۲-۱۸
کلمات کلیدی
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023