lack of association of cyp2e1 and cyp1a1 polymorphisms with osteoporosis in postmenauposal women

Lack of Association of CYP2E1 and CYP1A1 Polymorphisms With Osteoporosis in Postmenauposal Women

Osteoporosis is a metabolic bone disease affecting mostly elderly women. As metabolizing enzymes, the roles of few cytochromes have been studied in osteoporosis development. The aim of this study was to assess for the first time the association of CYP2E1 and CYP1A1 polymorphisms and osteoporosis in postmenopausal women. 112 postmenopausal women presenting osteoporosis and 93 age and sex matched...

investigation of association between tlr4 gene polymorphisms and osteoporosis in postmenauposal turkish women

the study of aaag repeat polymorphism in promoter of errg gene and its association with the risk of breast cancer in isfahan region

چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...

Association of CYP1A1 and CYP2E1 gene polymorphisms with prostate cancer in a Lebanese population

*Corresponding Author E-mail: [email protected] Tel.:+961 3 48 69 15; Fax +961 5 46 07 96 The present study investigates the association of the genetic polymorphisms of cytochromes P450 (CYP) 1A1 and 2E1 with prostate cancer (PCa), which is among the most common cancers in Lebanon and many countries. Prostate cancer is a multifactor disease where genetic polymorphisms of genes involved...

CYP1A1, CYP2E1 and EPHX1 polymorphisms in sporadic colorectal neoplasms

AIM To investigate the contribution of polymorphisms in the CYP1A1, CYP2E1 and EPHX1 genes on sporadic colorectal cancer (SCRC) risk. METHODS Six hundred forty-one individuals (227 patients with SCRC and 400 controls) were enrolled in the study. The variables analyzed were age, gender, tobacco and alcohol consumption, and clinical and histopathological tumor parameters. The CYP1A1*2A, CYP1A1*...

Lack of Association of SP110 Gene Polymorphisms with Pulmonary Tuberculosis in Golestan Province, Iran

ABSTRACT           Background and Objectives: Mycobacterium tuberculosis is the causative agent of pulmonary tuberculosis, a main public health problem that results in 1.5 million deaths annually. A number of epidemiological studies suggested that host genetic factors could play a main role in susceptibility to tuberculosis infection. SP110 is an i...