safety of anti-tnf-α therapy in patients with psoriasis and concomitant hepatitis c virus infection

The safety of anti-TNF therapy in patients with hepatitis B and C virus infection

Anti-TNF-directed therapies were introduced into clinical practice almost 15 years ago, heralding a new era in the treatment of various autoimmune or autoinf lammatory diseases, such as rheumatoid arthritis (RA), spondyloarthropathies (ankylosing spondylitis and psoriatic arthritis), psoriasis and inflammatory bowel diseases (Crohn’s disease and ulcerative colitis) [1]. This era – now referred ...

The Absence of Hepatitis C Virus Infection Among Patients with Hepatitis B virus in Mashhad, Iran

Background and Aims: Many studies have provided evidence for the role of hepatitis B and C viruses in the development of liver cancer. Although the routine treatment is available for both conditions, no definite guideline is available to treat patients dually infected with HBV and HCV. This study was performed to determine the frequency of HBV/HCV-coinfection in Mashhad, North-East of Iran. Mat...

CHARACTERISTICS AND PREVALENCE OF OCCULT HEPATITIS B VIRUS INFECTION IN PATIENTS WITH HEPATITIS C IN IRAN

 ABSTRACT Background: Hepatitis B virus (HBV) infection in patients who lack detectable hepatitis B surface antigen (HBsAg) is called occult hepatitis B infection. Such infections have been frequently identified in patients with chronic hepatitis Cliver disease, but their prevalence is not known. Methods: 207 patients with chronic hepatitis C who were HCV -RNA and antiHCV positive were stu...

Seroprevalence of Human Immunodificiency Virus (HIV) and Hepatitis C Infection In Hemophilic Patients In Iran

  Background and Objective: Although transfusion therapy has lead to great improvement in longevity for hemophiliacs, but there have been tragic setbacks especially from transmission of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) .HIV was reported to increase the rate of HCV-related liver failure by 4.2 times. In this study, we aimed to determine the seroprevalence of HIV an...

Experience With Anti–TNF-α Therapy in Dermatologic Immune-Mediated Inflammatory Disorders Psoriasis: Evidence for the Efficacy and Safety of Anti–TNF-α Treatment

Sero-Epidemiology of Hepatitis E Infections in patients with chronic Hepatitis C virus infection in Jahrom, Southern Iran

Background and Aims: Co-infection of hepatitis E virus (HEV) in chronic hepatitis C virus (HCV) infected patients can develop and increase liver disease and hepatic complications in the world. The purpose of this study was to assess the prevalence of HEV infection in patients suffering from chronic HCV infection. Materials and Methods: Cross-sectional study testing anti-HEV antibodies in serum...