synthesis, anti-bacterial and anti-fungal evaluation of 3-(substitutedphenyl)-n-(4h-1,2,4-triazol-4 yl)acrylamide
نویسندگان
چکیده
the series of 3-(substitutedphenyl)-n-(4h-1,2,4-triazol-4-yl)acrylamide compounds were prepared byreaction of 4-amino-1,2,4-triazole with acetyl chloride followed by claisen-schmidt condensation reactionwith different aromatic aldehydes. the structures of new compounds were confirmed by ir, 1h-nmr and13c-nmr spectral data. anti-bacterial and anti-fungal activities were evaluated and compared with thestandard drugs, some compounds of the series exhibited promising anti-microbial and anti-fungal activitycompared to standard drugs.
منابع مشابه
Synthesis, Anti-bacterial and Anti-fungal evaluation of 3-(Substitutedphenyl)-N-(4H-1,2,4-triazol-4 yl)acrylamide
The Series of 3-(Substitutedphenyl)-N-(4H-1,2,4-triazol-4-yl)acrylamide compounds were prepared byreaction of 4-amino-1,2,4-Triazole with Acetyl Chloride followed by Claisen-Schmidt Condensation reactionwith different aromatic aldehydes. The structures of new compounds were confirmed by IR, 1H-NMR and13C-NMR spectral data. Anti-bacterial and Anti-fungal activities were evaluated and compared wi...
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عنوان ژورنال:
journal of the iranian chemical researchجلد ۵، شماره ۳، صفحات ۱۸۷-۱۹۵
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