preparation of epoxy alcohols from cis and trans 2-(1-cyclohexenyl cyclohexanol and 2-cyclohexylidene cyclohexanone
نویسندگان
چکیده
epoxyalcohols are useful intermediates in complex organic synthesis, and recently they have been recognized as versatile intermediates for synthesis of natural products. the treatments of cis and trans 2-(1-cyclohexenyl) cyclohexanol, separately with paranirto perbenzoic acid gave the corresponding 2-(1- cyclohexenyl) cyclohexanol oxide. on the other hand, 2-cyclohexylidene cyclohexanol oxide was prepared in two ways. the structure of all the compounds confirmed via ir, nmr spectroscopy, and position of hydrogen bonding was examined with ir spectroscopy. nucleophilic opening of the corresponding compounds by various nucleophilic is under study.
منابع مشابه
Effect of Alkyl Substituents on the Hydrogen Catalytic Osmylation of Cis and Trans 2-Cyclohexene-Cyclohexanol
Catalytic osmylation of cis and trans 2-cyclohexene-cyclohexanol (1a) and (1b) are carried out in the presence of N-methyl morpholine-N-oxide. Under the same conditions, only the cis isomer reacted, leading to triol (3). The steric hindrance of the equatorial OH group probably prevents the trans isomer from entering into such reaction. Triol (3) was also obtained from the reduction of the d...
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عنوان ژورنال:
علومجلد ۱۸، شماره ۴۵، صفحات ۹۰۵-۹۱۰
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