n-glucosides: new phase-ii metabolites of two barbiturates
نویسندگان
چکیده
the new phase-ii n-glucoside metabolites of butobarbitone and pentobarbitone are identified and quantified in human urine after single doses of these drugs. the identification and quantification of these metabolites were carried out by mass spectroscopy technique (accurate mass measurement and high voltage scanning). it was found that the butobarbitone n-glucoside comprised 26% of the dose with tl/2= 44h, while the pentobarbitone n-glucoside was 43% with t1/2= 40h.
منابع مشابه
N-GLUCOSIDES: NEW PHASE-II METABOLITES OF TWO BARBITURATES
The new phase-II N-glucoside metabolites of butobarbitone and pentobarbitone are identified and quantified in human urine after single doses of these drugs. The identification and quantification of these metabolites were carried out by mass spectroscopy technique (accurate mass measurement and high voltage scanning). It was found that the butobarbitone N-glucoside comprised 26% of the dos...
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عنوان ژورنال:
medical journal of islamic republic of iranجلد ۶، شماره ۱، صفحات ۶۳-۶۶
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