organophosphate-induced chronic toxicity in occupationally exposed workers

organophosphate chronic toxicity has been evaluated in this study. biological screening for organophosphate insecticide-exposed workers is mostly recommended for mixers, loaders, formulators and spraymen. we have studied 17 occupationally exposed persons to pesticides. using ellman's colorimetric method, their plasma cholinesterase activities have been measured. results show that the appearance of some of the symptoms of chronic organophosphate toxicity depends on the extent of plasma cholinesterase activity reduction. our results also indicate that headache, weakness, nervousness, memory difficulty, tremors, insomnia and dizziness are• the main problems demonstrated in these workers.