evaluation of oral ginger efficacy against postoperative nausea and vomiting: a randomized, double - blinded clinical trial

conclusions: use of ginger was effective at decreasing postoperative nausea. ginger could be used as a safe antiemetic drug at post operation. results: mean nausea score at 2 hours post operation was significantly lower in the experimental group (p= 0.04). mean nausea score at 4 and 6 hours post operation was lower in the experimental group; however, there was no significant difference between the groups at any time post operation. the frequencies of nausea in the experimental group at 2 and 6 hours post operation were lower than that in the placebo group, however, at 2 hours post operation, it was borderline significant (p = 0.05) there was no significant differences between two group in the intensity of vomiting at any time. objectives: the aim of this study was to determine the effect of ginger on intensity of nausea and vomiting after surgical procedures. patients and methods: this study was a randomized, double blinded, clinical trial. 160 eligible patients were randomly assigned into experimental or placebo groups. the experimental group received 4 capsules containing 250 mg ginger and placebo group received 4 placebo capsules 1 hour before surgery. the severity of nausea and vomiting was measured at 2, 4, 6 hours post operation using visual analogue scale and a structured questionnaire. the data were analyzed by independent t - test, mann-whitney u test, chi –square and gee using spss 16 and stata version 11. background: postoperative nausea and vomiting is one of the most common side effects associated with surgical procedures.