coma blisters in the setting of quetiapine overdose: case report and review of literature

نویسندگان

timothy j. wiegand university of rochester medical center , strong memorial hospital, rochester, usa

rachel m. gorodetsky university of rochester medical center , strong memorial hospital, rochester, usa.department of pharmacy practice, d’youville college school of pharmacy, buffalo, usa

tamas r. peredy maine medical center, university of southern maine, portland, usa.northern new england poison center, portland, usa

چکیده

background: skin lesions and blistering in the overdose patient, most notably associated with barbiturate overdoses, are commonly referred to as coma blisters, 'barb blisters', or 'barb burns'. we present a patient who was noted to have skin lesions including bullae and blistering following a prolonged coma after quetiapine overdose. case report: a 27 year old male presented to our institution with the history of having ingested 7,200 mg of quetiapine in a suicide attempt up to 35 hours prior to being discovered. the patient was found comatose, and was noted to have multiple vesicles on his right ankle and a firm, erythematous plaque and bullae on his right thigh. discussion: sequelae related to prolonged immobility of any cause may include injury to muscle, vascular, microvascular and cutaneous structures. coma blisters differ from pressure ulcers in many ways and cannot be graded using the typical staging system. histopathologic analysis suggests an array of microvascular injuries which are secondary to direct pressure injury as well as specific drug effect. conclusion: this is the first description of a dermatologic manifestation attributed to coma from isolated quetiapine overdose. blister formation can be considered as a possible complication of quetiapine overdose.   how to cite this article: wiegand tj, gorodetsky rm, peredy tr. coma blisters in the setting of quetiapine overdose: case report and review of literature. asia pac j med toxicol 2013;2:153-6.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Coma Blisters in the Setting of Quetiapine Overdose: Case Report and Review of Literature

Background: Skin lesions and blistering in the overdose patient, most notably associated with barbiturate overdoses, are commonly referred to as coma blisters, ‘barb blisters’, or ‘barb burns’. We present a patient who was noted to have skin lesions including bullae and blistering following a prolonged coma after quetiapine overdose. Case report: A 27 year old male presented to our institution ...

متن کامل

ideological and cultural orientations in translation of narrative text: the case of hajji baba of isfahan

در میان عواملی که ممکن است ذهن مترجم را هنگام ترجمه تحت تأثیر قرار دهند، می توان به مقوله انتقال ایدئولوژی از طریق متن یا گفتمان اشاره کرد. هدف از این تحقیق تجزیه و تحلیل جنبه های ایدئولوژیکی و فرهنگی متن مبدأ انگلیسی نوشته جیمز موریه تحت عنوان سرگذشت حاجی بابای اصفهانی ( 1823) و ترجمه فارسی میرزا حبیب اصفهانی(1880) بوده است.

External ophthalmoplegia, alpha and spindle coma in imipramine overdose: case report and review of the literature.

A 13-year-old boy with imipramine overdose developed seizures, respiratory arrest, and coma. Abnormalities of oculovestibular reflexes, electroencephalograms, and brainstem auditory evoked potentials were monitored in relation to measurements of drug levels. An alpha-coma electroencephalographic pattern evolved into one evidencing spindle coma and eventually into a normal pattern. Prolonged bra...

متن کامل

contribution of setting to the study of characters and the main idea in e. brontes: wuthering heights and t. hardys: return of the native.

this thesis aims to adduce an unmitigated and comprehensive explication concerning the relationship of three significant elements of fiction: setting, chracter and theme. my research is basically placed on two outstanding novels of the 19th century: emily brontes wuthering heights and thomas hardys return of the native. my endeavour lies in studying the correlation among the three above-mention...

15 صفحه اول

Conservative Management of Dabigatran Overdose: Case Report and Review of Literature

Background: Direct thrombin inhibitors and factor Xa inhibitors are gaining popularity as alternatives to warfarin for patients requiring anticoagulation. Toxicity due to these medications is difficult to manage because overdose experience is very limited and there is no clear guidance on when or whether to use antidote in this setting. Case Presentation: A 50-year-old man with normal renal fu...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
asia pacific journal of medical toxicology

جلد ۲، شماره ۴، صفحات ۱۵۳-۱۵۶

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023