synthesis of graphene oxide-tio2 nanocomposite as an adsorbent for the enrichment and determination of rutin

objective(s):  in our study, graphene oxide-tio2 nanocomposite (go/tio2) was prepared and used for the enrichment of rutin from real samples for the first time.  materials and methods:   the synthesized go/tio2 was characterized by x-ray diffraction, scanning electron microscopy, and ft-ir spectra.  the enrichment process is fast and highly efficient. the factors including contact time, ph, and amount of go/tio2 affecting the adsorption process were studied.  results:   the maximum adsorption capacity for ciprofloxacin was calculated to be 59.5 mg/g according to the langmuir adsorption isotherm. the method yielded a linear calibration curve in the concentration ranges from 15 to 200 μg/l for the rutin with regression coefficients (r2) of 0.9990. the limits of detection (lods, s/n=3) and limits of quantification (loqs, s/n=10) were found to be 8 μg/land 28 μg/l, respectively. both the intra-day and inter-day precisions (rsds) were < 10% .  conclusion:  the developed approach offered wide linear range, and good reproducibility. owing to the diverse structures and unique characteristic, go/tio2 possesses great potential in the enrichment and analysis of trace rutin in real aqueous samples.