effect of streptokinase on short-term outcomes in the acute myocardial infarction with st-segment elevation

نویسندگان

awat feizi

ali nasr

hamid sanei

peyman mikaili

چکیده

acute coronary syndrome is one of the most prevalent cardiovascular diseases. the acute myocardial infarction is one of its kinds which embodies the indication of fibrinolysis. one of the fibrinolytic types mostly used in iran is streptokinase (sk). this study aims to study the short-term clinical outcomes after receiving sk.a prospective cohort study was conducted on 54 patients at hospitals affiliated to isfahan medical school. after discharging, within 30 days, patients were followed regarding the morality and major adverse cardiac events (mace) including re-mi, unstable angina, cerebrovascular accidents (cva) and doing revascularization. results were analyzed in both independent samples and chi-square by statistical t-tests using spss software. out of 54 patients, 25 individuals received sk versus 29 cases who did not receive that. in 30-day follow-up, no cva or re-mi was observed. in patients who did not receive sk, despite more deaths (14.2 % vs. 8 %) and mace (62% vs. 56 %), it was not statistically significant (p>0.05).in the present study, receiving sk did not cause to reduce the rate of mortality and mace in the time period of 30 days. however, it is suggested that a similar study with a larger size and also follow-up with long-term outcome be conducted.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Study of the Duration, Outcomes, and Related Factors of Reperfusion Therapy in Patients with ST-Segment Elevation Myocardial Infarction

Background and Objective: One of the most important advancements regarding the care of patients with acute myocardial infarction is the administration of anti-coagulation medicines (e.g., streptokinase). However, it must be noticed that this medicine requires rapid and timely administration. Moreover, Percutaneous Coronary Intervention (PCI) is increasingly used as a method of revascularization...

متن کامل

The streptokinase therapy complications and its associated risk factors in patients with acute ST elevation myocardial infarction

Acute myocardial infarction (AMI) is one of the main leading causes of mortality and morbidity. Despite the progress in the treatment of AMI, streptokinase is still being used in many countries. Because of the critical condition of patients with AMI and complications of streptokinase therapy, this study was performed to evaluate the pattern of adverse drug reaction (ADRs) induced by streptokina...

متن کامل

The streptokinase therapy complications and its associated risk factors in patients with acute ST elevation myocardial infarction

Acute myocardial infarction (AMI) is one of the main leading causes of mortality and morbidity. Despite the progress in the treatment of AMI, streptokinase is still being used in many countries. Because of the critical condition of patients with AMI and complications of streptokinase therapy, this study was performed to evaluate the pattern of adverse drug reaction (ADRs) induced by streptokina...

متن کامل

ST-Segment Elevation in Acute Myocardial Infarction

Four hundred and four patients who were admitted to the hospital with their first myocardial infarction within 24 hours of the onset of symptoms were studied. In 315 patients the ECG findings in 12 standards leads (I, II, aVF, aVR, aVL, V,-V6) showed the infarction to be in the anterior wall, the inferior wall, or in multiple areas. The patients in each of these three categories were further su...

متن کامل

comparison of short-term clinical outcome of non-st elevation versus st elevation myocardial infarction

background: studies on the prognosis of st elevation myocardial infarction (stemi) versus non-st elevation myocardial infarction (non-stemi) have shown different results. the present study was designed to compare the early outcome and left ventricular systolic function of patients with st and non-st elevation myocardial infarction. methods: the patients' information was derived from 10,065 cons...

متن کامل

Impact of Previous Stroke on Short-Term Myocardial Reinfarction in Patients With Acute ST Segment Elevation Myocardial Infarction

Myocardial reinfarction is frequent after ST-elevation myocardial infarction (STEMI). The incidence of previous stroke in STEMI patients is also high. We aim to evaluate the risk factors for short-term myocardial reinfarction in STEMI patients in a multicenter study.STEMI patients with chest pain onset within 12 hours in 247 hospitals in China were enrolled. Seven and 30-day follow-ups from adm...

متن کامل

منابع من

با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید


عنوان ژورنال:
journal of reports in pharmaceutical sciences

جلد ۳، شماره ۱، صفحات ۸۵-۸۹

کلمات کلیدی

میزبانی شده توسط پلتفرم ابری doprax.com

copyright © 2015-2023