ZNF341 controls STAT3 expression and thereby immunocompetence
نویسندگان
چکیده
منابع مشابه
Immunocompetence and allergy.
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In thymidylate synthase (TS), the invariant residue Asp-221 provides the only side chain that hydrogen bonds to the pterin ring of the cofactor, 5,10-methylene-5,6,7,8-tetrahydrofolate. All mutants of D221 except cysteine abolish activity. We have determined the crystal structures of two ternary complexes of the Escherichia coli mutant D221N. In a complex with dUMP and the antifolate 10-proparg...
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ژورنال
عنوان ژورنال: Science Immunology
سال: 2018
ISSN: 2470-9468
DOI: 10.1126/sciimmunol.aat4941