Zinc oxide nanoparticles embedded photo-crosslinkable PLA-block-PEG toward effective antibacterial coatings

Recent advances in PEG–PLA block copolymer nanoparticles

Due to their small particle size and large and modifiable surface, nanoparticles have unique advantages compared with other drug carriers. As a research focus in recent years, polyethylene glycol-polylactic acid (PEG-PLA) block copolymer and its end-group derivative nanoparticles can enhance the drug loading of hydrophobic drugs, reduce the burst effect, avoid being engulfed by phagocytes, incr...

Synthesis,characterization and Antibacterial Properties of Zinc Oxide Nanoparticles

Assessment of antioxidant and antibacterial activities of Zinc Oxide nanoparticles, Graphene and Graphene decorated by Zinc Oxide nanoparticles

Zinc Oxide nanoparticles (ZnO-NPs) and graphene carbon material, due to lower drug resistance, can replace antibiotics, and by decorating of graphene with Zn-NPs, their properties can be greatly improved. The purpose of this study was to evaluate the antioxidant and antibacterial effects of ZnO-NPs biosynthesized using Crocus Sativus petal extract, graphene and graphene decorated by ZnO-NPs bio...

Synthesis of protein-coated biocompatible methotrexate-loaded PLA-PEG-PLA nanoparticles for breast cancer treatment

Background: PLA-PEG-PLA triblock polymer nanoparticles are promising tools for targeted dug delivery. The main aim in designing polymeric nanoparticles for drug delivery is achieving a controlled and targeted release of a specific drug at the therapeutically optimal rate and choosing a suitable preparation method to encapsulate the drug efficiently, which depends mainly on the nature of the dru...

Photo-crosslinkable, deformable PMMA colloids

Polymeric nano andmicroparticles are finding widespread applications in materials and biological science. In all preparation methods pursued to date, the chemical stability of the particles is determined by the polymer system chosen. Usually, after particle synthesis, postprocessing with the aim of changing their stability is not possible. Therefore, one only has two choices: the synthesis of c...