منابع مشابه
Zinc: mechanisms of host defense.
Zinc deficiency in humans decreases the activity of serum thymulin (a thymic hormone), which is required for maturation of T-helper cells. T-helper 1 (Th(1)) cytokines are decreased but T-helper 2 (Th(2)) cytokines are not affected by zinc deficiency in humans. This shift of Th(1) to Th(2) function results in cell-mediated immune dysfunction. Because IL-2 production (Th(1) cytokine) is decrease...
متن کاملThe Journal of Nutrition Symposium: Micronutrient Regulation of Host-Pathogen Interactions Zinc: Mechanisms of Host Defense
Zinc deficiency in humans decreases the activity of serum thymulin (a thymic hormone), which is required for maturation of T-helper cells. T-helper 1 (Th1) cytokines are decreased but T-helper 2 (Th2) cytokines are not affected by zinc deficiency in humans. This shift of Th1 to Th2 function results in cell-mediated immune dysfunction. Because IL-2 production (Th1 cytokine) is decreased, this le...
متن کاملPulmonary host defense mechanisms.
T he major function of the respiratory system is to procure oxygen from the external environment and to eliminate carbon dioxide from the body at rates required by tissue metabolism. Unfortunately, ambient inspired air contains not only oxygen which is vital to survival, but also noxious gases and a multitude of particulates, including viable microorganisms, which the lungs must exclude to main...
متن کاملPathogenic Factors of P. gingivalis and the Host Defense Mechanisms
Periodontal diseases are the inflammatory diseases triggered specifically by some selected microorganisms, i.e., periodontopathic bacteria, accumulated in and around the gingival crevice. Among periodontopathic bacteria, Porphyromonas gingivalis, a black-pigmented gram-negative anaerobic rod, has been implicated as a major pathogen of chronic periodontitis (Hamada et al., 1991; Lamont & Jenkins...
متن کاملActivation of innate host defense mechanisms by Borrelia.
Borrelia is the causative agent of Lyme disease, a widespread disease with important health consequences. Immune-mediated mechanisms are believed to play a major role in both host defense and in late complications of Lyme disease. Recognition of Borrelia and the initial activation of the innate immune system are important for host defense, as well as modulation of adaptive responses. Several cl...
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ژورنال
عنوان ژورنال: The Journal of Nutrition
سال: 2007
ISSN: 0022-3166,1541-6100
DOI: 10.1093/jn/137.5.1345