Zinc finger proteins in psychiatric disorders and response to psychotropic medications
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چکیده
منابع مشابه
Sleep disturbances, psychiatric disorders, and psychotropic drugs
Brain neurotransmitter dysfunctions involved in the pathophysiological processes of psychiatric disorders are likely to be reflected by concomitant alterations in sleep continuity and architecture. Since the corrective effects of psychotropic drugs on dysfunctional neurotransmission systems can be evidenced through polysomnographic recordings, one may consider sleep as a kind of "window" on the...
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Zinc finger proteins acquire DNA-binding ability by Zn (II) complexation. In the zinc finger domain of the Cys2His2 type, each finger is approximately 30 amino acid residues long and consists of a simple ββα–fold stabilized by chelation of a zinc ion with the conserved Cys2His2 residues. A zinc finger motif of Cys2His2 offers an attractive framework for the design of a novel DNA-binding protein...
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ژورنال
عنوان ژورنال: Psychiatric Genetics
سال: 2019
ISSN: 0955-8829
DOI: 10.1097/ypg.0000000000000231