Zika virus: Vaccine initiatives and obstacles
نویسندگان
چکیده
منابع مشابه
Zika Virus: Diagnosis, Therapeutics, and Vaccine.
The current explosive epidemic of Zika virus in South and Central America, as well as the Caribbean, poses a global public health emergency. Here we comment on the challenges on development of better diagnosis and potential therapeutics and vaccine for Zika virus.
متن کاملZika Virus: Immunity and Vaccine Development
The emergence of Zika virus in the Americas and Caribbean created an urgent need for vaccines to reduce transmission and prevent disease, particularly the devastating neurodevelopmental defects that occur in utero. Rapid advances in Zika immunity and the development of vaccine candidates provide cautious optimism that preventive measures are possible.
متن کاملConsiderations for Developing a Zika Virus Vaccine.
Current prevention strategies fo cus on mosquito control, protec tion of the blood supply, barrier protection during sex, and other forms of contraception. When this explosive epidemic abates, Zika vi rus could remain endemic in many countries, where the risk to preg nant women, the general public, and travelers will persist. There fore, a safe and effective vaccine is essential. Developme...
متن کاملRecent Advances in Zika Virus Vaccine Development
Symbiosis Group Figure 1: Three different mechanisms of ADE (Antibody-dependent enhancement): A-receptors on virus particles bound by cross-reactive antibody get conformational change in structure that results in high affinity with the corresponding receptor on the host cell membrane. The corresponding receptor was not able to recognize the viral receptor before this conformational change. BThe...
متن کاملZika virus-like particle (VLP) based vaccine
The newly emerged mosquito-borne Zika virus poses a major public challenge due to its ability to cause significant birth defects and neurological disorders. The impact of sexual transmission is unclear but raises further concerns about virus dissemination. No specific treatment or vaccine is currently available, thus the development of a safe and effective vaccine is paramount. Here we describe...
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ژورنال
عنوان ژورنال: Medical Journal of Dr. D.Y. Patil University
سال: 2017
ISSN: 0975-2870
DOI: 10.4103/0975-2870.197899