Yield of Combined Impedance-pH Monitoring for Refractory Reflux Symptoms in Clinical Practice

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Yield of Combined Impedance-pH Monitoring for Refractory Reflux Symptoms in Clinical Practice

BACKGROUND/AIMS In patients with gastroesophageal reflux disease, persistent symptoms on proton pump inhibitor (PPI) therapy may be due to residual acid or non-acid reflux. Combined impedance-pH has been suggested to be superior to pH alone in the management of refractory patients to PPI. The utility of implementation of this technique in every day clinical practice is still unknown. The aim of...

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How Useful the Combined Impedance-pH Monitoring Is for Evaluation of Refractory Reflux Symptoms?

TO THE EDITOR: I read with great interest the paper entitled “Yield of combined impedance-pH monitoring for refractory reflux symptoms in clinical practice” by Karamanolis et al, which was published in April 2011 issue of Journal of Neurogastroenterology and Motility. Esophageal impedance pH monitoring allows detection of reflux of any composition (liquid or gas) and pH (acid, weakly acid or no...

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How Useful the Combined Impedance-pH Monitoring Is for Evaluation of Refractory Reflux Symptoms?: Author's Reply

TO THE EDITOR: We would like to appreciate the interest shown on our study by Dr. Cho. Our response to her queries is as follows: (1) We do agree that doubling the proton pump inhibitor (PPI) dose could be the most appropriate therapeutic strategy for gastroesophageal reflux disease (GERD) patients who are refractory to single dose of PPI before performing a pH-impedance measurement. However, p...

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Combined pH-metry/impedance monitoring increases the diagnostic yield in patients with atypical gastroesophageal reflux symptoms.

BACKGROUND Globus sensations, hoarseness and chronic cough are suggested to be atypical manifestations of Gastroesophageal Reflux Disease (GERD). The aim of the study was to investigate whether combined pH-metry and multichannel intraluminal impedance monitoring increases the diagnostic yield. METHODS 41 patients with atypical GERD symptoms were included in the study. Globus sensation was the...

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findings of impedance ph-monitoring in patients with atypical gastroesophageal reflux symptoms

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 aim : this study was designed to investigate about findings of impedance ph-monitoring in patients with atypical symptoms of gerd. background : the routine treatment with proton pump inhibitors is not very effective in patients with atypical symptoms of gastro-esophageal reflux disease (gerd). it may be due to non-acid ref...

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ژورنال

عنوان ژورنال: Journal of Neurogastroenterology and Motility

سال: 2011

ISSN: 2093-0879,2093-0887

DOI: 10.5056/jnm.2011.17.2.158