Yeasts of the Blastobotrys genus are promising platform for lipid-based fuels and oleochemicals production

Strains of the yeast genus Blastobotrys (subphylum Saccharomycotina) represent a valuable biotechnological resource for basic biochemistry research, single-cell protein, and heterologous protein production processes. Species this are dimorphic, non-pathogenic, thermotolerant, can assimilate variety hydrophilic hydrophobic substrates. These constitute oil platform in an emerging bio-based economy as oleaginous traits have been discovered recently. However, regulatory network lipogenesis these yeasts is poorly understood. To keep pace with growing market demands lipid-derived products, it critical to understand lipid biosynthesis unconventional pinpoint what governs preferential channelling carbon flux into lipids instead competing pathways. This review summarizes information relevant regulation metabolic pathways prospects engineering their application food, feed, beyond, particularly fatty acid-based fuels oleochemicals. • The biolipids by heterotrophic reviewed. Summary concerning metabolism highlighted. Special focus on importance diacylglycerol acyltransferases encoding genes improving made.