Yeast P-450 Responsible for Sterol Biosynthesis.
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چکیده
منابع مشابه
Sterol effects on phospholipid biosynthesis in the yeast strain GL7.
Cells of the yeast sterol auxotroph GL7 were grown on either ergosterol or cholesterol to mid-logarithmic phase and total membrane fractions prepared. Activities of phospholipid biosynthetic enzymes in the two cell types were determined. The rates of phosphatidyl-ethanolamine-phosphatidyl-choline-N-methyl transferase and acyl-CoA-alpha-glycerol-3-phosphate transcylase were significantly greater...
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The metabolism of cis-tramadol has been studied in human liver microsomes and in cDNA-expressed human cytochrome P-450 (CYP) isoforms. Human liver microsomes catalyzed the NADPH-dependent metabolism of tramadol to the two primary tramadol metabolites, namely, O-desmethyl-tramadol (metabolite M1) and N-desmethyl-tramadol (metabolite M2). In addition, tramadol was also metabolized to two minor se...
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catalyzing the conversion of the androgens, androstenedione (AD) and testosterone to the estrogens, estrone and estradiol, respectively. This process appears to proceed with three oxygenations of the androgens, each of which requires 1 mol of O2 and 1 mol of reduced nicotinamide adenine dinucleotide phosphate (NADPH). The 19-methyl group, as well as 1b and 2b-hydrogens, are eliminated in the th...
متن کاملSterol synergism in yeast.
Sterol synergism as previously observed [Dahl, C.E., Dahl, J.S. & Bloch, K. (1980) Biochemistry 19, 1462-1467] and defined as a greater-than-additive growth response to pairs of sterols by Mycoplasma capricolum [Dahl, J.S., Dahl, C.E. & Bloch, K. (1981) J. Biol. Chem. 256, 87-91] is now demonstrated in the yeast mutant GL7, which is auxotrophic for sterol and unsaturated fatty acid. Mutant cell...
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ژورنال
عنوان ژورنال: Journal of the agricultural chemical society of Japan
سال: 1992
ISSN: 0002-1407,1883-6844
DOI: 10.1271/nogeikagaku1924.66.158