منابع مشابه
Actin branches out in yeast
Actin branches out in yeast any of the same proteins control actin polymerization in budding yeast and mammalian cells. But budding yeast researchers—hampered by an emphasis on genetics and an inaccessible yeast cytoplasm dense with ribosomes and glycogen granules—have often lagged behind in providing structural descriptions based on electron microscopy (EM). This has fueled suspicions about wh...
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Many cell types, including fi broblasts and epithelial cells, move forward by forming an actin-rich membrane protrusion, called a lamellipodium, at the front of the cell. In the early 1990s, researchers thought that lamellipodial protrusion was driven by the polymerization of linear actin fi laments. In two JCB papers published in 1997 and 1999, however, Tatyana Svitkina and colleagues revealed...
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Signalling via tissue-specific receptors for fibroblast growth factor is important in tracheal branching and mesodermal patterning in Drosophila; both processes may involve a common primary response - detachment and directed migration of the target cells - that is conserved from worms to mammals.
متن کاملKidney development branches out.
For more than 40 years now, the developing kidney has served as a model paradigm for epithelial-mesenchymal interactions. The principles of inductive signaling, epithelial cell differentiation, and pattern formation are now being addressed with modern genetic and biochemical tools. In addition to the mammalian kidney organ culture model, both zebrafish and Xenopus laevis demonstrate great poten...
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ژورنال
عنوان ژورنال: Nature
سال: 1992
ISSN: 0028-0836,1476-4687
DOI: 10.1038/357190a0