منابع مشابه
Cytotoxic activity of proteins isolated from extracts of Corydalis cava tubers in human cervical carcinoma HeLa cells
BACKGROUND Corydalis cava Schweigg. & Koerte, the plant of numerous pharmacological activities, together with the studied earlier by our group Chelidonium majus L. (Greater Celandine), belong to the family Papaveraceae. The plant grows in Central and South Europe and produces the sizeable subterraneous tubers, empty inside, which are extremely resistant to various pathogen attacks. The Corydali...
متن کاملApplication of BACE1 immobilized enzyme reactor for the characterization of multifunctional alkaloids from Corydalis cava (Fumariaceae) as Alzheimer's disease targets.
In our ongoing study focused on Corydalis cava (Fumariaceae), used in folk medicine in the treatment of memory dysfunctions, we have investigated fifteen previously isolated alkaloids for their potential multifunctional activity on Alzheimer's disease (AD) targets. Determination of ß-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibition was carried out using a BACE1-Immobilized En...
متن کاملCorydalis tuber is the root of Corydalis yahusuo
WANG classified as Papaveraceae. Aqueous extract from Corydalis tuber is known to stimulate blood circulation and relieve pain. It has traditionally been used for the treatment of neuralgia, dysmenorrhea, and gastrointestinal spasm. The analgesic and spasmolytic properties of the Corydalis tuber are essentially ascribed to several alkaloids: DL-tetrahydropalmatine (THP), D-cotydaline, and coryd...
متن کاملNew cytotoxic tetrahydroprotoberberine-aporphine dimeric and aporphine alkaloids from Corydalis turtschaninovii.
Two new tetrahydroprotoberberine-aporphine dimeric alkaloids, corydaturtschines A (1) and B (2), and a new aporphine derivative, ethyl glausuccinate (3), together with 13 known protoberberine (4-16) and nine known aporphine alkaloids (17-25), were isolated from the tubers of Corydalis turtschaninovii. The structures of these new compounds were determined through spectral analyses, including ext...
متن کاملNew triterpenoids from the tubers of Corydalis ternata: structural elucidation and bioactivity evaluation.
Two new triterpene glycosides, coryternic acid 3-O-β-D-glucuronopyranoside (1) and coryternic acid 3-O-β-D-glucuronopyranoside-6'-O-methyl ester (2), were isolated from a MeOH extract of the tubers of Corydalis ternata. Acidic hydrolysis of 1 and 2 yielded a new triterpene as their aglycone, coryternic acid (3). The structures of these new compounds were determined through spectral analysis, in...
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ژورنال
عنوان ژورنال: J. Chem. Soc., Trans.
سال: 1893
ISSN: 0368-1645
DOI: 10.1039/ct8936300485