Xenobiotic-metabolizing enzymes in the skin of rat, mouse, pig, guinea pig, man, and in human skin models
نویسندگان
چکیده
منابع مشابه
Guinea-pig Skin in Tissue Culture
Small pieces of guinea-pig skin were exposed to a uniform field of microwaves at X-band (8,730 MHz). Measurements showed that 26%of the incident energy was reflected, 34% was absorbed, and the remaining 40% was transmitted. Absorbed energy was converted to heat, causing a rise in the temperature of the skin. After exposure to microwaves the skin was maintained in vitro on a nutrienmedium. Uptak...
متن کاملExpression of naked DNA in human, pig, and mouse skin.
The insertion and expression of genes in the epidermis may have a variety of therapeutic uses, including the treatment of skin diseases. Here we show that when both human skin organ cultures and human skin grafts on immunocompromised mice are injected with naked DNA, the DNA is taken-up and genes are expressed in the epidermis in a manner similar to both pig skin injected in vivo and injected p...
متن کاملEvaluation of Protective Effects of Nano-formulated Silymarin Against UV Radiation on Guinea Pig Skin
Background: As increased outdoor activities of people, they are more exposed to UV radiation, which causes harmful effects on skin. Silymarin has protective potentials against DNA damage and non-melanoma skin cancers, and also it has anti-oxidant, anti-inflammatory, and immune regulation characteristics. Nano formulation of plant material showed to be more effective than common ones. Object...
متن کاملHistaminase and its inhibitory factor in guinea pig skin.
The crude histaminase preparation obtained from guinea pig skin was fractionated by Sephadex G-200 at 4°C and 55°C. The histaminase activity corresponded to the descending limb of the :first peak of protein eluted just after void volume at 4°C and to the second peak at 55°C. The histaminase activity in the fractions eluted at 4°C was higher at 55°C than at 37°C. On the contrary, no significant ...
متن کاملKaryotype of Hairless Guinea pig
Chromosomal patterns of experimental animals are useful tools for cytogenetics research and animal breeding. Chromosome investigations of the hairless guinea pig are rare, therefore, karyotype of hairless guinea pigs (twelve male and female) was studied using metaphase spreads of bone marrows and G banding techniques. The chromosomes diploid number was 2n= 64 and polymorphism of three type chro...
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ژورنال
عنوان ژورنال: Archives of Toxicology
سال: 2014
ISSN: 0340-5761,1432-0738
DOI: 10.1007/s00204-014-1382-8