XCVII.—Nor-hyoscyamine and nor-atropine; alkaloids occurring in various solanaceous plants
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A Comprehensive Overview on Valuable Tropane Alkaloids: Scopolamine, Atropine, and Hyoscyamine
Tropane alkaloids such as scopolamine (C17H21NO4), atropine (C17H23NO3) and hyoscyamine (C17H23NO3) are the most important plant secondary metabolites in the pharmaceutical industry due to anticholinergic activity, competition with muscarinic receptors and also treating different human diseases. Scopolamine, hyoscyamine and atropine are the most important tropane alkaloids used as anticoagulant...
متن کاملNeither nalbuphine nor atropine possess special antishivering activity.
The special antishivering action of meperidine may be mediated by its kappa or anticholinergic actions. We therefore tested the hypotheses that nalbuphine or atropine decreases the shivering threshold more than the vasoconstriction threshold. Eight volunteers were each evaluated on four separate study days: 1) control (no drug), 2) small-dose nalbuphine (0.2 microg/mL), 3) large-dose nalbuphine...
متن کاملEnhanced secretion of tropane alkaloids in Nicotiana tabacum hairy roots expressing heterologous hyoscyamine-6beta-hydroxylase.
Hyoscyamine-6beta-hydroxylase (H6H; EC 1.14.11.11) catalyses oxidative reactions in the biosynthetic pathway leading from hyoscyamine to the more pharmaceutically valuable tropane alkaloid scopolamine. The h6h gene encoding H6H from Hyoscyamus niger was introduced, under the control of the CaMV 35S promoter, into non-hyoscyamine-producing Nicotiana tabacum and hyoscyamine-producing Hyoscyamus m...
متن کاملCytological Studies on Virus Diseases Op Solanaceous Plants '
Microscopical examinations of the tissues of mosaic-diseased plants have been made by numerous investigators since the earliest recognition of diseases of the plant virus group. With a few exceptions, these investigations have been confined to the study of a single virus disease upon a single species of host. It has now, however, come to be recognized that there are a number of different virus ...
متن کاملToxic Behaviour of Naturally Occurring Pyrrolizidine Alkaloids
The Pyrrolizidine Alkaloids (PAs) are the chemicals which are found in various plant species throughout the world. Pyrrolizidine alkaloids (PAs) are secondary metabolites those have been evolved as a powerful means in the plant defensive system against herbivores. Several studies are being performing to detect presence of PAs in the food and feed which are obtained from plants through direct or...
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ژورنال
عنوان ژورنال: J. Chem. Soc., Trans.
سال: 1912
ISSN: 0368-1645
DOI: 10.1039/ct9120100946