WU and KI Polyomaviruses Remain Orphans in Adults

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WU and KI polyomaviruses remain orphans in adults.

To the Editor—We read with interest the brief report by Barzon et al [1] showing that WU and KI polyomaviruses (WUPyV and KIPyV) reactivate and are frequently detectable in the brains of human immunodeficiency virus (HIV)–positive patients without being associated with progressive multifocal leukoencephalopathy. We also recently disproved such an association between novel polyomaviruses (includ...

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KI and WU Polyomaviruses in Children, France

James S. Gill,* Amy J. Ullmann,† Amanda D. Loftis,‡ Tom G. Schwan,§ Sandra J. Raffel,§ Merry E. Schrumpf, § and Joseph Piesman† *Iowa State University, Ames, Iowa, USA; †Centers for Disease Control and Prevention, Fort Collins, Colorado, USA; ‡Centers for Disease Control and Prevention, Atlanta, Georgia, USA; and §Rocky Mountain Laboratories of National Institutes of Health, Hamilton, Montana, USA

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Polyomaviruses KI and WU in Immunocompromised Patients with Respiratory Disease

Polyomaviruses KI (KIPyV) and WU (WUPyV) were recently identified, mainly in respiratory specimens from children. Among 200 patients with respiratory disorders admitted to Saint Louis Hospital, Paris, France, KIPyV was detected in 8% and WUPyV in 1%. KIPyV was significantly more frequent among human stem cell transplant patients (17.8% vs. 5.1%; p = 0.01).

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Recently, three novel human polyomaviruses KIPyV, WUPyV and MCPyV were uncovered in biological specimens of patients with different underlying clinical conditions. Although it is too early to draw firm conclusions on their role in human pathology, this finding has revitalized the scientific debate on the Polyomaviridae family and their relation to human disease. Seroepidemiological studies show...

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Prevalence of human KI and WU polyomaviruses in children with acute respiratory tract infection in China.

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ژورنال

عنوان ژورنال: The Journal of Infectious Diseases

سال: 2010

ISSN: 0022-1899,1537-6613

DOI: 10.1086/651379