Wrong place, wrong time: Runt-related transcription factor 2/SATB2 pathway in bone development and carcinogenesis

Right pace, wrong place.

Wrong place at the wrong time: A case of cervical embryonal rhabdomyosarcoma in pregnancy

•First case of NACT in cervical embryonal RMS•Second case occurring in pregnancy•Histological review outlining diagnostic difficulties.

Is general practice in the wrong PLACE?

In 1958 John Lykoudis, a dyspeptic smalltown Greek doctor, cured himself with antibiotics. Convinced of infective cause he prescribed his multiple antibiotic formulation ‘Elgaco’ to 30 000 patients with ulcer.1 Barry Marshall, credited with discovering the bacterial cause for ulcers, acknowledges Lykoudis.1 The JAMA considered that the association between acid and ulcer was proof of causation a...

Wrong-side/wrong-site, wrong-procedure, and wrong-patient adverse events: Are they preventable?

HYPOTHESIS Wrong-side/wrong-site, wrong-procedure, and wrong-patient adverse events (WSPEs) are devastating, unacceptable, and often result in litigation, but their frequency and root causes are unknown. Wrong-side/wrong-site, wrong-procedure, and wrong-patient events are likely more common than realized, with little evidence that current prevention practice is adequate. DESIGN Analysis of se...

Lipids in the Wrong Place: Visceral Fat and Nonalcoholic Steatohepatitis

There is substantial evidence in both animal (1,2) and human models of lipodystrophy (3) that the accumulation of excessive fat in ectopic sites that normally lack adipose tissue, such as the skeletal muscle and the liver, may trigger whole-body insulin resistance. This article will review the evidence showing the condition of fatty liver as an independent and perhaps better indicator of diseas...