Wound botulism in an injecting drug user in Scotland

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Outbreak of wound botulism in injecting drug users in Germany, October-December 2005.

Between October and December 2005, 16 cases of wound botulism were notified to the health authorities of North Rhine-Westphalia, Germany. All patients were injecting drug users (IDU) and the epidemiological investigations suggested contaminated injection drugs as the most probable source of infection. Clostridium botulinum was cultivated from clinical samples of six patients and molecular typin...

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Wound Botulism in Injection Drug Users

To the Editor: Infections are the most frequent and serious wound complications in injection drug users (IDUs). Wound botulism is primarily caused by Clostridium botulinum (1) and was fi rst observed in IDUs in New York in 1982 (2). It results from the introduction of C. botulinum spores into a wound and their multiplication, germination, in situ synthesis, and secretion of toxin under anaerobi...

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Necrotising fasciitis with pronounced local oedema is described in an injecting drug user. Clostridium novyi was an unexpected single pathogen isolated from infected tissue. The patient was among a cluster of cases, all injecting drug users, presenting with toxaemia and soft tissue infection. The causal role and pathogenicity of C novyi is discussed.

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An investigation is currently underway to explore and control an outbreak of Bacillus anthracis among drug users (mainly injecting) in Scotland. Contaminated heroin or a contaminated cutting agent mixed with the heroin is considered to be the most likely source and vehicle of infection. Heroin users have been advised of the risk. The risk to the general public is regarded as very low.

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ژورنال

عنوان ژورنال: Weekly releases (1997–2007)

سال: 2001

ISSN: 9999-1233

DOI: 10.2807/esw.05.41.01850-en