Woman with Hypomagnesemia and Hypocalcemia

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Woman with hypomagnesemia and hypocalcemia.

A 71-year-old woman was referred to the endocrinology clinic after several years of unresolved hypomagnesemia that required numerous hospital admissions to receive intravenous magnesium. She previously presented with palpitations on 3 occasions, and once with diarrhea and vomiting. The blood tests on all 4 presentations demonstrated severe hypomagnesemia (Table 1). Her medical history included ...

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Hypomagnesemia predicts postoperative biochemical hypocalcemia after thyroidectomy

BACKGROUND To investigate the role of magnesium in biochemical and symptomatic hypocalcemia, a retrospective study was conducted. METHODS Less-than-total thyroidectomy patients were excluded from the final analysis. Identified the risk factors of biochemical and symptomatic hypocalcemia, and investigated the correlation by logistic regression and correlation test respectively. RESULTS A tot...

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Familial Hypomagnesemia with Secondary Hypocalcemia Mimicking Neurodegenerative Disorder.

BACKGROUND Familial hypomagnesemia with secondary hypocalcemia is a genetic disorder of magnesium metabolism that presents with refractory seizures in infancy. CASE CHARACTERISTICS We herein report an infant with familial hypomagnesemia who presented as medically-refractory seizures and had cerebral atrophy on neuroimaging. Interestingly he had lost previous two siblings because of lack of co...

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Primary hypomagnesemia with secondary hypocalcemia in an infant.

A 2-month old girl was transferred from General Hos­ pital Kurunegala to the Lady Ridgeway Hospital (LRH) in September 1998 with a history of uncontrolled generalised fits from the age of 6 weeks. Before 6 weeks the baby-had been apparently normal. She is a product of a first cousin marriage. The other two children are in good health. The birth and neonatal histories were normal. The birth weig...

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Novel TRPM6 mutations in 21 families with primary hypomagnesemia and secondary hypocalcemia.

Primary hypomagnesemia with secondary hypocalcemia is a rare autosomal recessive disorder characterized by profound hypomagnesemia associated with hypocalcemia. Pathophysiology is related to impaired intestinal absorption of magnesium accompanied by renal magnesium wasting as a result of a reabsorption defect in the distal convoluted tubule. Recently, mutations in the TRPM6 gene coding for TRPM...

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ژورنال

عنوان ژورنال: Clinical Chemistry

سال: 2015

ISSN: 0009-9147,1530-8561

DOI: 10.1373/clinchem.2014.229005