Wolbachia and arbovirus inhibition in mosquitoes

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Wolbachia and arbovirus inhibition

1249 Arbovirus inhibition phenotype Arboviruses transmitted by mosquitoes have great importance in global health, owing to increasing ranges and impact and often with no effective vaccines or reliable prophylactics available. The most important is the flavivirus dengue virus (DENV), which occurs in 100 countries and causes tens of millions of cases of dengue fever annually, approximately half a...

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Arbovirus Prevalence in Mosquitoes, Kenya

Few studies have investigated the many mosquito species that harbor arboviruses in Kenya. During the 2006-2007 Rift Valley fever outbreak in North Eastern Province, Kenya, exophilic mosquitoes were collected from homesteads within 2 affected areas: Gumarey (rural) and Sogan-Godud (urban). Mosquitoes (n = 920) were pooled by trap location and tested for Rift Valley fever virus and West Nile viru...

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Determinants of Arbovirus Vertical Transmission in Mosquitoes

Vertical transmission (VT) and horizontal transmission (HT) of pathogens refer to parental and non-parental chains of host-to-host transmission. Combining HT with VT enlarges considerably the range of ecological conditions in which a pathogen can persist, but the factors governing the relative frequency of each transmission mode are poorly understood for pathogens with mixed-mode transmission. ...

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Tissue Barriers to Arbovirus Infection in Mosquitoes

Arthropod-borne viruses (arboviruses) circulate in nature between arthropod vectors and vertebrate hosts. Arboviruses often cause devastating diseases in vertebrate hosts, but they typically do not cause significant pathology in their arthropod vectors. Following oral acquisition of a viremic bloodmeal from a vertebrate host, the arbovirus disease cycle requires replication in the cellular envi...

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High Wolbachia density in insecticide-resistant mosquitoes.

Wolbachia symbionts are responsible for various alterations in host reproduction. The effects of the host genome on endosymbiont levels have often been suggested, but rarely described. Here, we show that Wolbachia density is strongly modified by the presence of insecticide-resistant genes in the common house mosquito, Culex pipiens. The Wolbachia density was estimated using a real-time quantita...

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ژورنال

عنوان ژورنال: Future Microbiology

سال: 2013

ISSN: 1746-0913,1746-0921

DOI: 10.2217/fmb.13.95