Wilms’ Tumor Protein WT1(‐KTS) inhibits Renin gene transcription
نویسندگان
چکیده
منابع مشابه
Tumor necrosis factor- inhibits renin gene expression
Todorov, Vladimir, Markus Müller, Frank Schweda, and Armin Kurtz. Tumor necrosis factorinhibits renin gene expression. Am J Physiol Regul Integr Comp Physiol 283: R1046–R1051, 2002. First published June 27, 2002; 10.1152/ajpregu.00142.2002.—Renin, produced in renal juxtaglomerular (JG) cells, is a fundamental regulator of blood pressure. Accumulating evidence suggests that cytokines may directl...
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Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...
متن کاملIn silico screening of G-Quadruplex Structures in Wilms tumor 1 Gene Promoter
Introduction: X-ray diffraction studies have revealed that guanines in a DNA stands may be arranged in quartet and form a structure called G-quadruplexs. Bioinformatics studies suggested the formation of G-quadruplex structure in human crucial genes, including Wilms tumor 1 (WT1). The aim of this study was to in silico analysis of the guanine-rich sequence in the promoter region of the WT1 gene...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2007
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.21.6.a896