منابع مشابه
Widespread ocular use of topical chloramphenicol: is there justifiable concern regarding idiosyncratic aplastic anaemia?
A theoretical but as yet not conclusively proved risk of chloramphenicol induced idiosyncratic aplastic anaemia exists with topical ophthalmic therapy, with the absolute, but highly improbable, maximum risk of death (equalling that of systemic therapy) being 1 in 50,000 to 90,000. To put this in realistic perspective, one must note that the comparable risk of fatal anaphylaxis resulting from pe...
متن کاملTopical chloramphenicol : have GPs
Sir, An editorial in the British Medical Journal (BMJ)1 on the use of chloramphenicol eye drops suggested that the risks of topical chloramphenicol were sufficient to warrant practitioners to prescribe an alternative, such as Framycetin or Fucidic Acid. We sent a postal questionnaire to 664 general practitioners (GPs) in the areas of Leeds, Guildford, and Cambridge to ascertain the influence th...
متن کاملTopical chloramphenicol for eye infections.
Topical chloramphenicol has been widely used in the treatment and prevention of superficial eye infections due to its broad spectrum of activity and low cost. The use of this drug has decreased considerably in the United States since the first case of aplastic anaemia associated with topical chloramphenicol was reported in the 1960s. This medication, however, is still widely used in many other ...
متن کاملReaction or infection: topical chloramphenicol treatment
Chloramphenicol is a topical treatment that is used widely, especially in wounds around the eyes. In our practice there have been a number of cases of delayed hypersensitivity to chloramphenicol that has been mismanaged initially as an infective cellulitis. We hope to share some of our experience of this uncommon reaction to highlight the delayed reaction that can occur with topical applicatio...
متن کاملThe effects of topical chloramphenicol and ciprofloxacin on conjunctival bacterial flora of healthy dogs
BACKGROUND: Normal bacterial flora of the conjunctiva, which inhibits growth of opportunistic organisms, has an important role in the prevention of ocular infections. If resident flora is inhibited by disease or long-term application of antibiotics, opportunistic pathogens overgrow, leading to disease. OBJECTIVES: The aim of this study was to investigate the effects of ophthalmic chloramphenico...
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ژورنال
عنوان ژورنال: British Journal of Ophthalmology
سال: 1996
ISSN: 0007-1161
DOI: 10.1136/bjo.80.9.854