Why is the Cold Agglutinin Reactive in Cold?
نویسندگان
چکیده
منابع مشابه
Cold agglutinin disease.
Cold agglutinin disease is a rare and poorly understood disorder affecting 15% of patients with autoimmune hemolytic anemia. We reviewed the clinical and pathologic features, prognosis, and management in the literature and describe our institutional experience to improve strategies for accurate diagnosis and treatment. Retrospective analysis identified 89 patients from our institution with cold...
متن کاملWhy is the centromere so cold?
Chromosomes are known to contain local hot and cold spots that undergo quite different rates of meiotic recombination. The question of why such regional variation in recombination rates exists on chromosomes holds a strange mix of intrigue and frustration for geneticists. One of the human chromosomes that has been carefully studied over the years in this regard is the X chromosome. These studie...
متن کاملCold Agglutinin Disease; A Laboratory Challenge
INTRODUCTION Autoimmune haemolytic anemia (AIHA) is a complex process characterized by an immune reaction against red blood cell self-antigens. The analysis of specimens, drawn from patients with cold auto-immune hemolytic anemia is a difficult problem for automated hematology analyzer. This paper was written to alert technologists and pathologists to the presence of cold agglutinins and its ef...
متن کاملHow I manage cold agglutinin disease.
Primary chronic cold agglutinin disease (CAD) is a clonal lymphoproliferative disorder accounting for 13-15% of autoimmune haemolytic anaemias. Significant advances have been made in treatment, which was largely unsuccessful until recently. The essential clinical, immunological and pathological features are reviewed, focusing on their relevance for therapy. Non-pharmacological management still ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Seibutsu Butsuri
سال: 1998
ISSN: 0582-4052,1347-4219
DOI: 10.2142/biophys.38.250