منابع مشابه
Why Cancer & Metabolism? Why now?
The identification of oncogenic driver mutations of many cancers by deep sequencing is validating the oncogene versus tumor suppressor paradigm of tumorigenesis. At the same time, there is a profound resurgence of interest in metabolism in the context of neoplasia, both at the whole-organism level with respect to the influence of caloric intake on cancer behavior, and at the cellular level, wit...
متن کاملWhy Cancer?
Throughout my career as a health economist, one issue has always been a mystery to me—why does cancer enjoy such a dominant position within healthcare systems throughout the world? The debate concerning the reconfiguration of the Cancer Drugs Fund (CDF), which is addressed in this journal [1], represents a microcosm of a much wider debate reflecting the complex and ever-changing interface betwe...
متن کاملWhy Cancer and Inflammation?
Central to the development of cancer are genetic changes that endow these "cancer cells" with many of the hallmarks of cancer, such as self-sufficient growth and resistance to anti-growth and pro-death signals. However, while the genetic changes that occur within cancer cells themselves, such as activated oncogenes or dysfunctional tumor suppressors, are responsible for many aspects of cancer d...
متن کاملWhy Another Cancer Journal?
Why do we need yet another cancer journal? An excellent question, of course, in light of the profusion of general as well as specialized cancer journals in recent times. An easy answer would simply be to say that this journal will be better than the rest; however a less glib (and probably more accurate) response is simply that there is currently an explosion of new techniques and approaches in ...
متن کاملWhy vitamin D for cancer patients?
UNLABELLED Several epidemiological, pre-clinical and clinical studies support Vitamin D as a preventive and therapeutic cancer agent. BACKGROUND Vitamin D and cancer: calcitriol, the biologically active form of vitamin D (1,25(OH)D), exerts its effects mainly through binding to nuclear vitamin D receptor (VDR). Calcitriol has been shown to be an anti-proliferative, pro-differentiation, pro-ap...
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ژورنال
عنوان ژورنال: PharmacoEconomics
سال: 2016
ISSN: 1170-7690,1179-2027
DOI: 10.1007/s40273-016-0413-0