Which serum cortisol after high dose short synacthen test, 30 or 60 min?
نویسندگان
چکیده
منابع مشابه
Response to 'Determining the utility of the 60-min cortisol measurement in the short Synacthen test'.
OBJECTIVE Despite the widespread use of the short synacthen test (SST), there remains no clear consensus on sampling times for the measurement of serum cortisol that best determines adrenal reserve. We set out to establish whether there is any value in measuring serum cortisol at 60 min following administration of synacthen. DESIGN Retrospective data analysis of 500 SST results measuring 0, 3...
متن کاملDiagnosis of secondary adrenal insufficiency in patients with hypothalamic-pituitary disease: comparison between serum and salivary cortisol during the high-dose short synacthen test.
OBJECTIVE Accurate assessment of adrenal function is essential in patients with hypothalamic-pituitary-adrenal (HPA) disease. The measurement of salivary cortisol (SaC) instead of serum cortisol (SeC) offers several advantages, such as the determination of the free hormone. We evaluated the diagnostic value of SeC and SaC both unstimulated and during a high-dose short synacthen test (HDT) in co...
متن کاملNormal cortisol response on low-dose synacthen (1 microg) test in children with Prader Willi syndrome.
INTRODUCTION It has been postulated that central adrenal insufficiency (CAI), resulting from hypothalamic dysfunction, may contribute to the increased unexplained death rates in Prader Willi syndrome (PWS). A study using the overnight metyrapone test reported a 60% prevalence of CAI in children with PWS. We used a low-dose Synacthen test to screen for CAI in children with PWS. METHODS We stud...
متن کاملSalivary cortisol in low dose (1 microg) ACTH test in healthy women: comparison with serum cortisol.
To date, a single report has appeared on the use of salivary cortisol for adrenal function testing with a low dose ACTH, although 1 microg has become preferred as a more physiological stimulus than the commonly used 250 microg ACTH test. Our present study was aimed to obtain physiological data on changes of free salivary cortisol after 1 microg ACTH stimulation. This approach was compared with ...
متن کاملPlasma "cortisol" response to Synacthen in patients on long-term small-dose prednisone therapy.
Material Patients.-39 patients were studied, all but one of whom had taken prednisone 5 mg./day for periods of from 8 weeks to 8 years. One patient (Case 31) had her dose increased from 5 to 7 mg./day 8 months before the test. With the exception of two who had polymyalgia rheumatica, all had rheumatoid arthritis. Of these 39 patients, nineteen were selected at random and studied again after a y...
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ژورنال
عنوان ژورنال: Endocrine Abstracts
سال: 2014
ISSN: 1479-6848
DOI: 10.1530/endoabs.35.p1