Which incision is better for Lewis to Brown Norway rat liver transplantation, transverse or midline?

Orthotopic rat liver transplantation (OLT) is a complex microsurgical procedure extensively applied to basic science, myriad complications can occur, but incision-related self-biting has not been reported after OLT. For the project of tolerance induction through stem cells, we performed OLT from Lewis Brown Norway (BN) rats as an acute rejection model and divided study was into transverse incision group (n = 15) midline 22), while cyclosporine A subcutaneously injected for 10-day immunosuppression use, lidocaine cream used pain-relieving. The recipient survival wound status were primary endpoint this study. group, 30-day rate 40% (6/15), occurred in 13 cases 7–39 days, degree 1 biting cases, 2 cases. 3 10 which caused death or euthanasia, 86.7% (13/15), 100% (22/22), no severe occurred. There significant differences (p 0.0003) < 0.01) between two groups. In conclusion, behavior occurs due incisional injury, severely pain-causing; one effective avert occurrences.