Where there is inflammation, treatment may reduce disability progression – Yes

Where there is smoke, there is fire.

The ankle-brachial index (ABI), a ratio of systolic blood pressure measured at the ankle and the brachial artery, is a simple noninvasive screening test used to diagnose peripheral arterial disease (PAD). PAD affects over 12 million people in the United States and its prevalence increases with increasing age (1,2). Patients with an abnormal ABI, defined as 0.90 or 1.40, are at increased risk of...

Yes , Virginia , There is a Santa Claus

The bulk of this paper is a finegrained critical analysis of a single argument. Such detailed treatment, unusual though it is in a journal article, is warranted for a number of reasons, I think . First, a clear understanding of the particular argument in question demands close attention. Different arguments can, and do, warrant different degrees, kinds, and depths of analysis, and the one under...

"Yes, Virginia, there is a Santa Claus".

Is There Evidence That Oral Hypoglycemic Agents Reduce Cardiovascular Morbidity/Mortality? Yes

A though type 2 diabetes is a heterogeneous condition encompassing multiple metabolic and vascular alterations, it can be easily described as a disease characterized by chronic hyperglycemia and increased cardiovascular (CV) risk. Hyperglycemia is the diagnostic criterion for diabetes, the target for antidiabetic therapy, and, together with A1C, the marker of glycemic control. Progressive worse...

Where there is a will there is a way

Peritonitis was a significant problem for our peritoneal dialysis patients in 2003. In January 2004, we initiated a continuous quality improvement project to address the problem. Our project took 18 months to complete. We developed many action items. Our first step was to analyze the data to ensure accuracy, and also to determine the causative organism that contributed most to the problem. The ...