Wheezing phenotypes in childhood

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Wheezing phenotypes in childhood.

There can no longer be any doubt that, within the spectrum On this dubious basis, a third phenotype with a peak prevalence at six years was identified between the group of of wheezing disorders of childhood, several distinct phenoearly transient wheezers and later atopic asthmatic subjects. types can be recognised. Although clinicians have been The distinction between children who wheezed in th...

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Steroid responsiveness and wheezing phenotypes.

Oral corticosteroids are the cornerstone of management of acute moderate or severe asthma whilst preventive inhaled corticosteroids are the mainstay of the preventive management of children with asthma. Yet, variation in the magnitude of response to corticosteroids has been observed. There is increasing evidence that preschool-aged children with viral-induced asthma may display a certain degree...

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Peak flow variability, methacholine responsiveness and atopy as markers for detecting different wheezing phenotypes in childhood.

BACKGROUND There is increasing evidence that wheezing during childhood may be a heterogeneous condition, and that different forms of wheezing may be associated with different risk factors and prognosis. The aim of this study was to determine if measures of airway lability and of atopy could identify distinct wheezing phenotypes during childhood. METHOD In a cohort of children followed from bi...

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Original Contribution Childhood Wheezing, Asthma, Allergy, Atopy, and Lung Function: Different Socioeconomic Patterns for Different Phenotypes

Identifying preventable exposures that lead to asthma and associated allergies has proved challenging, partly because of the difficulty in differentiating phenotypes that define homogeneous disease groups. Understanding the socioeconomic patterns of disease phenotypes can help distinguish which exposures are preventable. In the present study, we identified disease phenotypes that are susceptibl...

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Childhood Wheezing, Asthma, Allergy, Atopy, and Lung Function: Different Socioeconomic Patterns for Different Phenotypes

Identifying preventable exposures that lead to asthma and associated allergies has proved challenging, partly because of the difficulty in differentiating phenotypes that define homogeneous disease groups. Understanding the socioeconomic patterns of disease phenotypes can help distinguish which exposures are preventable. In the present study, we identified disease phenotypes that are susceptibl...

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ژورنال

عنوان ژورنال: Thorax

سال: 1997

ISSN: 0040-6376

DOI: 10.1136/thx.52.11.936