What is an epigenetic transgenerational phenotype?
نویسندگان
چکیده
منابع مشابه
Environmentally induced epigenetic transgenerational inheritance of phenotype and disease.
Environmental epigenetics has an important role in regulating phenotype formation or disease etiology. The ability of environmental factors and exposures early in life to alter somatic cell epigenomes and subsequent development is a critical factor in how environment affects biology. Environmental epigenetics provides a molecular mechanism to explain long term effects of environment on the deve...
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Copyright: © 2013 Vaiserman AM . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Over the past decade, there is substantive evidence that adverse consequences of early-life environmental stresses, such as chem...
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Transgenerational epigenetic effects include all processes that have evolved to achieve the nongenetic determination of phenotype. There has been a long-standing interest in this area from evolutionary biologists, who refer to it as non-Mendelian inheritance. Transgenerational epigenetic effects include both the physiological and behavioral (intellectual) transfer of information across generati...
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Recent fi ndings in the emerging fi eld of transgenerational epigenetic inheritance suggest that the lifestyle choices and experiences of an individual have biological implications for offspring not yet conceived. Studies show that diet, drugs, and even social experiences can lead to life-long changes in gene expression. Some changes in gene expression are passed down to future generations. The...
متن کاملTransgenerational epigenetic inheritance
Marisa Bartolomei University of Pennsylvania, USA Stefan Beck University College London, UK Christoph Bock University of Vienna, AT Liran Carmel Hebrew University of Jerusalem, IL Katharina Gapp Sanger Institute, Cambridge, UK Johannes Graeff Ecole Polytechnique Fédérale, Lausanne, CH Carlos Guerrero-Bosagna Linköping University, SE Eva Jablonka Tel Aviv University, IL Josep Chillarón Hospital ...
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ژورنال
عنوان ژورنال: Reproductive Toxicology
سال: 2008
ISSN: 0890-6238
DOI: 10.1016/j.reprotox.2007.09.001