What Identity Crisis? Rapidly Mutating Y-STRs Facilitate Differentiation of Males
نویسندگان
چکیده
منابع مشابه
Mutation Rates and Discriminating Power for 13 Rapidly-Mutating Y-STRs between Related and Unrelated Individuals
Rapidly Mutating Y-STRs (RM Y-STRs) were recently introduced in forensics in order to increase the differentiation of Y-chromosomal profiles even in case of close relatives. We estimate RM Y-STRs mutation rates and their power to discriminate between related individuals by using samples extracted from a wide set of paternal pedigrees and by comparing RM Y-STRs results with those obtained from t...
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The Y chromosome is one of the smallest human chromosomes with an average size of 60 million base pairs (Mb). Between X and Y chromosomes, exchange is limited to small pseudoautosomal regions (PAR) of the X-Y pair (see Figure 1). During male meiosis, recombination only takes place at the most distal short arm (PAR 1) and at the tip of the Y chromosome long arm (PAR 2). For most of its length (t...
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15 صفحه اولToward Male Individualization with Rapidly Mutating Y-Chromosomal Short Tandem Repeats
Relevant for various areas of human genetics, Y-chromosomal short tandem repeats (Y-STRs) are commonly used for testing close paternal relationships among individuals and populations, and for male lineage identification. However, even the widely used 17-loci Yfiler set cannot resolve individuals and populations completely. Here, 52 centers generated quality-controlled data of 13 rapidly mutatin...
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ژورنال
عنوان ژورنال: Human Mutation
سال: 2014
ISSN: 1059-7794
DOI: 10.1002/humu.22412